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当代简明综述 2021:间质性肺疾病。

Contemporary Concise Review 2021: Interstitial lung disease.

机构信息

Department of Respiratory Medicine, St. Vincent's University Hospital, Dublin, Ireland.

School of Medicine, University College Dublin, Dublin, Ireland.

出版信息

Respirology. 2022 Jul;27(7):539-548. doi: 10.1111/resp.14278. Epub 2022 May 5.

DOI:10.1111/resp.14278
PMID:35513341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9320947/
Abstract

The last 2 years have presented previously unforeseen challenges in pulmonary medicine. Despite the significant impact of the SARS-CoV-2 pandemic on patients, clinicians and communities, advances in the care and understanding of interstitial lung disease (ILD) continued unabated. Recent studies have led to improved guidelines, better understanding of the role for antifibrotics in fibrosing ILDs, prognostic indicators and novel biomarkers. In this concise contemporary review, we summarize many of the important studies published in 2021, highlighting their relevance and impact to the management and knowledge of ILD.

摘要

过去 2 年,肺部医学面临了前所未有的挑战。尽管 SARS-CoV-2 大流行对患者、临床医生和社区造成了重大影响,但间质性肺疾病(ILD)的护理和认识方面的进展仍在继续。最近的研究导致了更好的指南、对纤维化性ILD 中抗纤维化药物作用的更好理解、预后指标和新的生物标志物。在这篇简明的当代综述中,我们总结了 2021 年发表的许多重要研究,强调了它们与ILD 管理和知识的相关性和影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/841e/9320947/783c21fd83f3/RESP-27-539-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/841e/9320947/783c21fd83f3/RESP-27-539-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/841e/9320947/38c8385c3eff/RESP-27-539-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/841e/9320947/8f5eb7489660/RESP-27-539-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/841e/9320947/783c21fd83f3/RESP-27-539-g003.jpg

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本文引用的文献

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Eur Respir J. 2022 Jun 16;59(6). doi: 10.1183/13993003.01396-2021. Print 2022 Jun.
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Serial decline in lung volume parameters on computed tomography (CT) predicts outcome in idiopathic pulmonary fibrosis (IPF).计算机断层扫描(CT)上肺容积参数的连续下降可预测特发性肺纤维化(IPF)的结局。
Eur Radiol. 2022 Apr;32(4):2650-2660. doi: 10.1007/s00330-021-08338-2. Epub 2021 Oct 30.
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Biomarker signatures for progressive idiopathic pulmonary fibrosis.
代谢驱动的糖基化代表了间质性肺疾病的治疗机会。
Front Immunol. 2024 Mar 14;15:1328781. doi: 10.3389/fimmu.2024.1328781. eCollection 2024.
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The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis.成纤维细胞中 CALD1、CDH2 和 POSTN 的基因表达与特发性肺纤维化有关。
Front Immunol. 2024 Feb 2;15:1275064. doi: 10.3389/fimmu.2024.1275064. eCollection 2024.
5
Role of Telomere Length in Survival of Patients with Idiopathic Pulmonary Fibrosis and Other Interstitial Lung Diseases.端粒长度在特发性肺纤维化和其他间质性肺疾病患者生存中的作用
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Association of the 6-minute walking test ratio and difference with pulmonary function in patients with interstitial lung disease.6 分钟步行试验比和差与间质性肺疾病患者肺功能的相关性。
Saudi Med J. 2023 Oct;44(10):1000-1005. doi: 10.15537/smj.2023.44.10.20220940.
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Respir Care. 2023 Nov 25;68(12):1662-1674. doi: 10.4187/respcare.11147.
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4
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