Falkenhagen U, Hacker K, Rehbock A, Handschuck I, Nimmich W
Z Urol Nephrol. 1986 Nov;79(11):609-18.
Of 168 urine sediments, which were obtained from 55 patients with chronic pyelonephritis in the course of 3 years when a significant bacteriuria with E. coli was present, we demonstrated antibody-loaded bacteria in 81 cases (48.21%). In the active stage of the disease with 54.10% were found significantly more than in the inactive with 32.61%. In obstructive chronic pyelonephritis the positive rate was 54.79% in contrast to 43.16% in non-obstructive chronic pyelonephritis. While in the active stage of the obstructive chronic pyelonephritis with 57.41% more antibody-containing bacteria were excreted than with 47.31% in the inactive stage, the positive rate in the active stage of the non-obstructive chronic pyelonephritis was with 54.47% significantly increased in contrast to 22.22% in the inactive stage. 25.71% of the patients excreted only ACB+-, 34.29% only ACB(-)- and 40% ACB+- and ACB(-)-germs in the course of the disease. The ACB-positive quote was in rough forms with 62.50% statistically significantly increased in contrast to 45.54% in O-typable and 42.86% in non-O-typable strains. In the ACB+- group the immunofluorescence titres to the homologous strain and the C3-activator in the serum as well as the urine lysozyme were significantly higher than in the ACB(-)-group.
在3年期间从55例慢性肾盂肾炎患者中获取了168份尿沉渣样本,这些患者当时存在大肠杆菌引起的显著菌尿,我们在81例(48.21%)中发现了抗体负载细菌。疾病活动期的检出率为54.10%,显著高于非活动期的32.61%。梗阻性慢性肾盂肾炎的阳性率为54.79%,而非梗阻性慢性肾盂肾炎为43.16%。梗阻性慢性肾盂肾炎活动期排出含抗体细菌的比例为57.41%,高于非活动期的47.31%;非梗阻性慢性肾盂肾炎活动期的阳性率为54.47%,显著高于非活动期的22.22%。25.71%的患者在病程中仅排出ACB+ -,34.29%仅排出ACB(-) -,40%排出ACB+ -和ACB(-) -细菌。ACB阳性率在粗糙型中为62.50%,与O型可分型菌株的45.54%和非O型可分型菌株的42.86%相比有统计学显著升高。在ACB+ -组中,血清中针对同源菌株和C3激活剂的免疫荧光滴度以及尿溶菌酶均显著高于ACB(-) -组。