Persson Canice Drea, Djärv Therese, Rödström Maria Ygland
Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Emergency Department, Karolinska University Hospital, Stockholm, Sweden.
Resusc Plus. 2022 Apr 27;10:100238. doi: 10.1016/j.resplu.2022.100238. eCollection 2022 Jun.
Higher rates of mortality following an in-hospital cardiac arrest (IHCA) has been shown during nights and weekends, changes in staff density and composition has been suggested as a possible explanation. Changes in hospital staffing patterns are also common during holiday periods.
To investigate whether holiday periods are associated with decreased survival following an IHCA.
All patients ≥18 years who experienced an IHCA at Karolinska University Hospital between 2006 and 2019 were included. Patients were identified via and data was collected from the Swedish Registry for Cardiopulmonary Resuscitation. Holiday was defined as two periods, a seven-week summer period and an approximately two-week Christmas period. The primary outcome was return of spontaneous circulation (ROSC), secondary survival to hospital discharge. Logistic regression was performed to calculate odds ratio (OR) with 95% confidence intervals (CI), adjustment was done for known confounders.
Out of 1936 registered cases, 264 (14%) occurred during holiday periods. Patient and event characteristics were similar on holidays compared to non-holidays. Both ratio for ROSC (45% and 55%, respectively) and survival (25% and 32% respectively) was poorer during holiday periods Adjusted OR for ROSC and survival was poorer during holiday periods compared non-holiday periods (OR 0.69 [95% CI, 0.53-0.92] and OR 0.69 [95% CI, 0.49-0.96], respectively).
Outcomes after IHCA was poorer during holiday periods compared to non-holiday periods even if patient and event characteristics was similar. Further research is needed to better understand to what degree staffing patterns and other factors contribute to the observed difference.
研究表明,在夜间和周末发生院内心脏骤停(IHCA)后的死亡率更高,有人提出工作人员密度和组成的变化可能是一个解释。在节假日期间,医院的人员配置模式变化也很常见。
调查节假日期间是否与院内心脏骤停后的生存率降低有关。
纳入2006年至2019年期间在卡罗林斯卡大学医院经历院内心脏骤停的所有18岁及以上患者。通过瑞典心肺复苏登记处识别患者并收集数据。节假日定义为两个时间段,一个为期七周的夏季时段和一个约两周的圣诞节时段。主要结局是自主循环恢复(ROSC),次要结局是出院存活。进行逻辑回归以计算比值比(OR)及其95%置信区间(CI),并对已知的混杂因素进行调整。
在1936例登记病例中,264例(14%)发生在节假日期间。与非节假日相比,节假日期间的患者和事件特征相似。节假日期间ROSC的比例(分别为45%和55%)和生存率(分别为25%和32%)均较差。与非节假日相比,节假日期间ROSC和生存率的调整后OR较差(分别为OR 0.69 [95% CI,0.53 - 0.92]和OR 0.69 [95% CI,0.49 - 0.96])。
即使患者和事件特征相似,院内心脏骤停后节假日期间的结局也比非节假日期间差。需要进一步研究以更好地了解人员配置模式和其他因素在何种程度上导致了观察到的差异。