Elyasi Zahra, Safaei Ghomi Javad, Najafi Gholam Reza, Zand Monfared Mohammad Reza
Department of Chemistry, Qom Branch, Islamic Azad University Post Box: 37491-13191 Qom I. R. Iran
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan Iran.
RSC Adv. 2020 Dec 15;10(72):44159-44170. doi: 10.1039/d0ra08647a. eCollection 2020 Dec 9.
Although poly (ionic liquids) (PILs) have attracted great research interest owing to their various applications, the performance of nanoporous PILs has been rarely developed in the catalysis field. To this end, a micro-mesoporous PIL with acid-base bifunctional active sites was designed and fabricated by two different polymerization protocols including hydrothermal and classical precipitation polymerization in this paper. Based on our observations, hydrothermal conditions (high temperature and pressure) enabled the proposed sonocatalyst to possess a great porous structure with a high specific surface area ( : 315 m g) and thermal stability (around 450 °C for 45% weight loss) through strengthening cross-linking. In a comparative study, the preferred nanoporous PIL was selected and utilized as the sonocatalyst in a multicomponent reaction of isatins, primary amines, and thioglycolic acid. In the following, a variety of new and known pharmaceutical spiro-4-thiazolidinone derivatives were synthesized at room temperature and obtained excellent yields (>90%) within short reaction times (4-12 min) owing to the substantial synergistic effect between ultrasound irradiation and magnetically separable catalyst.
尽管聚离子液体（PILs）因其各种应用而引起了极大的研究兴趣，但纳米多孔PILs在催化领域的性能却鲜有开发。为此，本文通过水热和经典沉淀聚合两种不同的聚合方法设计并制备了一种具有酸碱双功能活性位点的微介孔PIL。基于我们的观察，水热条件（高温高压）通过加强交联使所提出的声催化剂具有高比表面积（：315 m²/g）和热稳定性（约450°C时失重45%）的优异多孔结构。在一项对比研究中，选择了优选的纳米多孔PIL并将其用作靛红、伯胺和巯基乙酸多组分反应中的声催化剂。接下来，在室温下合成了各种新的和已知的药物螺-4-噻唑烷酮衍生物，由于超声辐照和磁性可分离催化剂之间的显著协同效应，在短反应时间（4-12分钟）内获得了优异的产率（>90%）。
