基于与不同杂环体系相连的1,3,5-三嗪核心合成新型星形分子作为新型杂化分子。
Synthesis of novel star-shaped molecules based on a 1,3,5-triazine core linked to different heterocyclic systems as novel hybrid molecules.
作者信息
Diab Hadeer M, Salem Mostafa E, Abdelhamid Ismail A, Elwahy Ahmed H M
机构信息
Department of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt
出版信息
RSC Adv. 2020 Dec 14;10(72):44066-44078. doi: 10.1039/d0ra09025e. eCollection 2020 Dec 9.
The synthesis of novel star-shaped compounds based on an -triazine core and linked to hexahydroacridinediones, pyrimido[4,5-]quinolones, 1-isoquinolino[2,1-]quinolines, tetrahydro-4-chromenes, dihydropyrano[2,3-]pyrazoles, thiazole, or benzothiazole as new hybrid molecules through Michael and Hantzsch reactions is reported. For this purpose, 2,4,6-tris(4-formylphenoxy)benzaldehyde was used as a versatile precursor.
报道了基于三嗪核心并通过迈克尔反应和汉茨希反应与六氢吖啶二酮、嘧啶并[4,5 - ]喹啉酮、1 - 异喹啉并[2,1 - ]喹啉、四氢 - 4 - 色烯、二氢吡喃并[2,3 - ]吡唑、噻唑或苯并噻唑相连的新型星形化合物的合成，作为新的杂化分子。为此，使用2,4,6 - 三(4 - 甲酰基苯氧基)苯甲醛作为通用前体。
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