Friedman M, Grybauskas V, Toriumi D M, Skolnik E, Chilis T
Ann Otol Rhinol Laryngol. 1987 Mar-Apr;96(2 Pt 1):163-9. doi: 10.1177/000348948709600205.
Reconstruction of the subglottis is usually required after resection of cricoid cartilage or tracheal tissue in cases of trauma, subglottic stenosis, or invasive thyroid carcinoma. There are multiple techniques available for reconstruction of the subglottic larynx, but most of them have a high rate of complications or graft failure. We have found the sternocleidomastoid myoperiosteal flap to be an ideal means of reconstruction. In an experimental study, we performed subglottic reconstruction using the sternomastoid myoperiosteal flap on 15 mongrel dogs to determine the presence of bone formation versus calcified fibrous scar. Radiologic studies suggested apparent metaplastic bone formation at the graft site, and histologic studies confirmed this. Functionally, 12 dogs had stable airways without stridor or subglottic narrowing. Three dogs died of complications. With successful reconstruction of large defects in the canine subglottis, attempts to repair large subglottic and tracheal defects in the human are feasible.
在创伤、声门下狭窄或侵袭性甲状腺癌病例中,环状软骨或气管组织切除术后通常需要进行声门下重建。目前有多种技术可用于声门下喉重建,但大多数技术并发症发生率高或移植物失败率高。我们发现胸锁乳突肌肌骨膜瓣是一种理想的重建方法。在一项实验研究中,我们对15只杂种犬使用胸锁乳突肌肌骨膜瓣进行声门下重建,以确定骨形成与钙化纤维瘢痕的情况。放射学研究提示移植物部位有明显的化生骨形成,组织学研究证实了这一点。功能方面,12只犬气道稳定,无喘鸣或声门下狭窄。3只犬死于并发症。随着犬声门下大缺损重建的成功,尝试修复人类的大的声门下和气管缺损是可行的。