Primary Large Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Gallbladder.

Primary lymphoma of the gallbladder (GB) is a rare condition, and very few cases have been reported so far. Diagnosis is usually made after surgery of suspicious GB mass, which is often difficult to differentiate from GB carcinoma. The GB wall does not contain lymphoid tissue, and tumors arise at the submucosal layer. Stone disease and chronic inflammation may contribute to its pathogenesis. Treatment consists of surgical resection followed by adjuvant therapy in selected cases. We present a case of an unusual, large-sized mucosa-associated lymphoid tissue (MALT) lymphoma of the GB.