Jean D, François P, Chouraqui J P, Rouhan D, Andrini P, Rambaud P
Arch Fr Pediatr. 1987 Jan;44(1):17-9.
The detection of group B streptococcal soluble antigens was performed in 139 newborn infants suspected of infection. A qualitative agglutination test of sensitized latex particles (Wellcogen Strep B) was performed in the urine. The diagnosis of group B streptococcal infection was assessed by retrospective analysis of patient files using previously defined criteria. The correlation between the agglutination test result and the presence or absence of streptococcal infection was statistically significant; the test had a sensitivity of 81%, specificity of 97%, positive predictive value of 76% and negative predictive value of 98%. This study confirms the interest of such a test in the early diagnosis of group B streptococcal infection in infants.
对139名疑似感染的新生儿进行了B族链球菌可溶性抗原检测。采用尿液中致敏乳胶颗粒定性凝集试验（Wellcogen B族链球菌检测试剂）。通过回顾性分析患者病历，采用先前定义的标准评估B族链球菌感染的诊断。凝集试验结果与链球菌感染的有无之间的相关性具有统计学意义；该试验的灵敏度为81%，特异度为97%，阳性预测值为76%，阴性预测值为98%。本研究证实了此类检测对婴儿B族链球菌感染早期诊断的价值。
