Burden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.
School of Public Health, University of the Western Cape, Cape Town, South Africa.
Pan Afr Med J. 2022 Feb 17;41:140. doi: 10.11604/pamj.2022.41.140.32104. eCollection 2022.
Multimorbidity is defined as the co-existence of multiple health conditions in one person. However, its use in research has been predominantly applied to non-communicable diseases, because research was conducted almost exclusively in developed countries. More recently, infectious diseases of long duration, such as human immunodeficiency virus (HIV), have also been included in the conceptualization of multimorbidity. While multimorbidity is a growing area of research globally; much less is known about the phenomenon in low and middle-income countries (LMICs) where disease burdens are heavily impacted by HIV. Health systems and services tend to be constrained in LMICs and information on disease patterns are important to better prioritize services. This commentary aims to describe the changing conceptualization of multimorbidity, the dearth of research into multimorbidity in LMICs and how the knowledge generated by research in LMICs can contribute to the global understanding of multimorbidity. LMICs can play a key role in the implementation of integration research.
多发病被定义为一个人同时存在多种健康状况。然而,它在研究中的应用主要集中在非传染性疾病上,因为研究几乎完全在发达国家进行。最近,像人类免疫缺陷病毒(HIV)这样持续时间较长的传染病也被纳入多发病的概念化中。尽管多发病是一个在全球范围内不断发展的研究领域;但在疾病负担受 HIV 严重影响的低收入和中等收入国家(LMICs),人们对这种现象的了解要少得多。卫生系统和服务在 LMICs 中往往受到限制,了解疾病模式的信息对于更好地确定服务重点很重要。本评论旨在描述多发病概念化的变化、LMICs 中多发病研究的缺乏,以及 LMICs 中的研究产生的知识如何有助于对多发病的全球理解。LMICs 可以在实施综合研究方面发挥关键作用。