Saw K Y, Anz A W, Jee Csy, Ramlan A, Dawam A, Low S F
Department of Orthopaedic Surgery, Kuala Lumpur Sports Medicine Centre, Kuala Lumpur, Malaysia.
Department of Orthopaedics, Andrews Institute for Orthopaedics and Sports Medicine, Gulf Breeze, United States.
Malays Orthop J. 2022 Mar;16(1):134-137. doi: 10.5704/MOJ.2203.022.
End-stage ankle arthritis represents an "unmet medical need", awaiting an appropriate time for joint arthroplasty or arthrodesis. We report three cases of end-stage ankle arthritis treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells, resulting in reversal of the ankle arthritis. The improvement in clinical outcome measure scores (Ankle Osteoarthritis Scale total score) with a minimum two-year follow-up were comparable to total ankle replacement (TAR), arthroscopic ankle arthrodesis (AAA) and open ankle arthrodesis (OAA).
终末期踝关节关节炎代表一种“未满足的医疗需求”，等待着进行关节置换术或关节融合术的合适时机。我们报告了三例终末期踝关节关节炎病例，按照为膝关节软骨形成所制定的原则，采用自体外周血干细胞进行治疗，结果踝关节关节炎得到了逆转。经过至少两年的随访，临床结局测量评分（踝关节骨关节炎量表总分）的改善情况与全踝关节置换术（TAR）、关节镜下踝关节融合术（AAA）和开放性踝关节融合术（OAA）相当。
