Tsuji Hideto, Tamura Ken-Ichi, Arakawa Yuki
Department of Environmental and Life Sciences, Graduate School of Engineering, Toyohashi University of Technology Tempaku-cho Toyohashi Aichi 441-8580 Japan
RSC Adv. 2019 Mar 1;9(13):7094-7106. doi: 10.1039/c9ra00255c.
The present paper proposes a versatile strategy for the synthesis and mechanical property manipulation of networked biodegradable polymeric materials composed of well-defined alternating soft and hard domains. As an example of the strategy, we selected biodegradable poly(l-lactide) (PLLA) and poly(ε-caprolactone) (PCL) as the hard and soft components, respectively, and synthesized networked biodegradable polymeric materials composed of well-defined alternating PLLA and PCL domains with different l-lactide (LLA) unit contents crosslinking of well-defined four-armed diblock copolymers of PLLA and PCL (4-C-L). The strategy reported here, which is also applicable to non-biodegradable polymeric materials, successfully facilitated the synthesis of the networked biodegradable materials composed of alternating hard and soft domains and their mechanical properties of the synthesized materials were largely manipulated by the LLA unit contents of the precursor four-armed diblock 4-C-L copolymers. Moreover, the crystallization behavior and thermal properties of 4-C-L copolymers before and after crosslinking were investigated and discussed.
本文提出了一种通用策略，用于合成和调控由明确的交替软硬段组成的网络化可生物降解聚合物材料的机械性能。作为该策略的一个实例，我们分别选择了可生物降解的聚（L-丙交酯）（PLLA）和聚（ε-己内酯）（PCL）作为硬段和软段，并通过交联具有不同L-丙交酯（LLA）单元含量的明确的四臂双嵌段共聚物PLLA和PCL（4-C-L），合成了由明确的交替PLLA和PCL段组成的网络化可生物降解聚合物材料。本文报道的策略也适用于非可生物降解聚合物材料，成功地促进了由交替软硬段组成的网络化可生物降解材料的合成，并且合成材料的机械性能在很大程度上受前体四臂双嵌段4-C-L共聚物的LLA单元含量的调控。此外，还对交联前后4-C-L共聚物的结晶行为和热性能进行了研究和讨论。
