Doughty D, Lambert G D, Hirst A, Marks A M, Plowman P N
Br J Radiol. 1987 Mar;60(711):269-78. doi: 10.1259/0007-1285-60-711-269.
The total-body irradiation (TBI) technique at St Bartholomew's Hospital has been developed to improve dose homogeneity within the patient. Using a standard 6 MV linear accelerator in an orthodox-sized treatment room, the midpoint doses in head, neck, shoulders, mid-mediastinum, pelvis, knees and ankles are +/- 5% of that of the umbilicus in our current technique. This homogeneity has been achieved by a four-field technique, a reproducible patient set-up, careful use of a new bolus material and an additional beam-flattening filter mounted near the machine head. In addition, thermoluminescent dosimetric data collected at a test irradiation before TBI are used to influence field weightings and further improve dosimetry. This individualised and empirical TBI technique has dosimetric advantages over theoretical TBI dosimetric considerations in reducing dose gradients within the patient. These advantages are discussed.
圣巴塞洛缪医院的全身照射（TBI）技术已得到改进，以提高患者体内的剂量均匀性。在一个常规尺寸的治疗室中使用标准的6兆伏直线加速器，在我们目前的技术中，头部、颈部、肩部、中纵隔、骨盆、膝盖和脚踝处的中点剂量是脐部剂量的±5%。这种均匀性是通过四野技术、可重复的患者摆位、小心使用一种新的等效物材料以及在机头附近安装一个额外的射束平坦化滤过器来实现的。此外，在TBI之前的一次测试照射中收集的热释光剂量测定数据被用于影响射野权重并进一步改善剂量测定。这种个体化的经验性TBI技术在减少患者体内剂量梯度方面比理论上的TBI剂量测定考虑具有剂量学优势。本文将讨论这些优势。
