水引发多组分反应合成4-色烯杂化支架
Water-triggered union of multi-component reactions towards the synthesis of a 4-chromene hybrid scaffold.
作者信息
Kumaravel Kandhasamy, Rajarathinam Balakrishnan, Vasuki Gnanasambandam
机构信息
Department of Chemistry, Pondicherry University Puducherry-605014 India
出版信息
RSC Adv. 2020 Aug 6;10(49):29109-29113. doi: 10.1039/d0ra05105e. eCollection 2020 Aug 5.
Abstract
An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four new heterocycles ten covalent bonds in a single step.
摘要
据报道，在室温下的水中，通过前所未有的多组分反应结合，能从简单反应物构建出带有吡唑和吡喃并吡唑的4-色烯。这种创新策略整合了两种不同的四组分反应（4CRs），这些反应瞬间发生，一步形成四个新的杂环和十个共价键。
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