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经皮冠状动脉介入治疗中初次经皮冠状动脉介入治疗时的入路交叉的预测因素和围手术期结局——来自波兰 ORPKI 注册研究的当代报告。

Predictors and periprocedural outcomes of access crossover during primary percutaneous coronary interventions - a contemporary report from the Polish ORPKI registry.

机构信息

Collegium Medicum, Jan Kochanowski University, Kielce, Poland.

2nd Department of Cardiology, Świętokrzyskie Cardiology Center, Kielce, Poland.

出版信息

Kardiol Pol. 2022;80(7-8):799-805. doi: 10.33963/KP.a2022.0121. Epub 2022 May 6.

Abstract

BACKGROUND

The radial artery became preferable access for percutaneous coronary interventions (PCI). The latest European Society of Cardiology guidelines strongly recommended transradial access in patients with ST-segment elevation myocardial infarction (STEMI). Though, in a significant portion of the coronary artery, invasive procedure crossover to femoral is necessary.

AIMS

This study aimed to determine the ratio, risk factors, and periprocedural outcomes of crossover from radial to femoral access during PCI in a contemporary STEMI registry.

METHODS

Based on data from the Polish registry ORPKI, we analyzed 90245 patients with a diagnosis of STEMI that were intended to be treated invasively via transradial access between 2014 and 2019.

RESULTS

In 1484 (1.6 %) individuals, a switch to femoral access was necessary during the procedure. The most important independent predictors of vascular crossover were female sex, previous coronary artery bypass graft, class 3 and 4 of the Killip scale, left main disease, as well as any complications during coronary angiography. In that cohort, the risk of bleeding at the puncture site was over 20-fold higher. Major disparities in periprocedural outcomes (death during procedure, cardiac arrest during PCI, Thrombolysis In Myocardial Infarction (TIMI) after PCI, and no-reflow) between these groups resulted from disparities in initial characteristics, and they were not associated with crossover itself.

CONCLUSIONS

Even though the risk of crossover to femoral is currently low, it appears to be indispensable to sustain operators' experience both in radial and femoral approaches to achieve the best outcomes in these patients.

摘要

背景

桡动脉已成为经皮冠状动脉介入治疗(PCI)的首选入路。欧洲心脏病学会的最新指南强烈建议 ST 段抬高型心肌梗死(STEMI)患者采用经桡动脉入路。然而,在很大一部分冠状动脉中,需要经皮穿刺股动脉入路进行介入治疗。

目的

本研究旨在确定在当代 STEMI 注册研究中,经桡动脉入路行 PCI 时,从桡动脉到股动脉入路的转换比例、危险因素和围手术期结局。

方法

根据波兰 ORPKI 注册研究的数据,我们分析了 2014 年至 2019 年间拟行经桡动脉入路侵入性治疗的 90245 例 STEMI 患者的数据。

结果

在 1484 例(1.6%)患者中,在手术过程中需要转换为股动脉入路。血管转换的最重要独立预测因素是女性、先前的冠状动脉旁路移植术、Killip 分级 3 级和 4 级、左主干疾病以及冠状动脉造影期间的任何并发症。在该队列中,穿刺部位出血的风险增加了 20 多倍。这些患者在围手术期结局(手术期间死亡、PCI 期间心脏骤停、PCI 后 TIMI 分级、无复流)方面存在显著差异,这是由于初始特征的差异所致,与转换本身无关。

结论

尽管目前股动脉入路的转换风险较低,但似乎有必要维持术者在桡动脉和股动脉入路方面的经验,以实现这些患者的最佳结局。

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