Division of Nephrology, Children's Hospital of Richmond, 1000 E Broad St, Room 5-448, Richmond, VA, 23219, USA.
Division of Nephrology, Ann & Robert H Lurie Children's Hospital, Chicago, IL, USA.
Pediatr Nephrol. 2023 Feb;38(2):557-564. doi: 10.1007/s00467-022-05584-4. Epub 2022 May 6.
Initiation of continuous kidney replacement therapy (CKRT) greater than 20% fluid overload is associated with increased morbidity and mortality. We aimed to reduce the number of patients initiated on CKRT greater than 20% fluid overload by 50% in one year by implementation of a quality improvement initiative.
This is a prospective quality improvement study set in a pediatric ICU of an urban children's hospital of patients initiated on CKRT over 2 years. The intervention included creation of an electronic health record order for daily calculation of net percent fluid overload, incorporation into daily rounds, and education programs tailored to physicians and bedside nursing. We measured adherence with the new order set, percent fluid overload at CKRT initiation, days on CKRT, timing of first nephrology consultation, and death prior to discharge.
A total of 32% of patients were initiated on CKRT greater than 20% fluid overload pre-initiative and 9% post-initiative, a 72% reduction over 13 months. Patients initiated on CKRT greater than 20% fluid overload had median CKRT course of 8 (IQR 4-14) vs. 22 days (IQR 13.5-62).
Creating a system using EHR with education may reduce initiation of CKRT after development of severe fluid overload. A higher resolution version of the Graphical abstract is available as Supplementary information.
开始持续肾脏替代治疗(CKRT)时超过 20%的液体超负荷与发病率和死亡率增加有关。我们的目标是通过实施一项质量改进计划,在一年内将开始 CKRT 时超过 20%液体超负荷的患者数量减少 50%。
这是一项在一家城市儿童医院儿科重症监护病房进行的前瞻性质量改进研究,研究对象为在 2 年期间开始接受 CKRT 的患者。干预措施包括创建电子病历医嘱,以每天计算净液体超负荷百分比,将其纳入每日查房,并为医生和床边护士制定专门的教育计划。我们测量了新医嘱集的依从性、CKRT 开始时的液体超负荷百分比、CKRT 持续时间、首次肾病咨询的时间以及出院前的死亡情况。
在实施前,有 32%的患者开始接受 CKRT 时超过 20%的液体超负荷,实施后为 9%,13 个月内减少了 72%。开始接受 CKRT 时超过 20%液体超负荷的患者的中位 CKRT 疗程为 8(IQR 4-14)天,而开始接受 CKRT 时未超过 20%液体超负荷的患者为 22(IQR 13.5-62)天。
通过创建一个使用电子病历和教育的系统,可能会减少在出现严重液体超负荷后开始 CKRT。可提供更高分辨率的图表摘要版本作为补充信息。