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环境温度暴露与中国新乡皮肤科疾病门诊就诊风险的时间序列分析。

Ambient temperature exposure and risk of outpatient visits for dermatologic diseases in Xinxiang, China: a time-series analysis.

机构信息

Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, School of Public Health, Xinxiang Medical University, Xinxiang, 453003, Henan Province, China.

National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, 100021, China.

出版信息

Int J Biometeorol. 2022 Jul;66(7):1487-1493. doi: 10.1007/s00484-022-02297-z. Epub 2022 May 6.

Abstract

The effect of ambient temperature on dermatologic diseases has received widespread attention. Previous studies have shown that ambient temperature might affect specific dermatologic diseases, but results were inconsistent. This study aims to assess the short-term effect of ambient temperature on outpatient visits due to dermatologic diseases (DMs) in Xinxiang, China. Daily DMs outpatient visits, mean temperature, mean relative humidity, and air pollution data of Xinxiang were retrieved from January 1, 2015, to December 31, 2018. A distributed lag nonlinear model (DLNM) was applied to analyze the effect of ambient temperature on DMs outpatients. We controlled several potential confounding factors such as the long-term trend, public holiday, day of the week, humidity, and air pollutants (NO, PM). Finally, two more stratification analysis was conducted by age and gender. A total of 164,270 outpatients of DMs were enrolled during our study, and the daily mean visits were 113. The estimated effect of temperature on DMs was nonlinear. Heat temperature would exacerbate outpatients of dermatologic diseases. With a reference median temperature (17 °C), the effect of temperature on DMs was most pronounced at lag0-14; exposure to heat (32 °C, 99th) was associated with 1.565 (95% CI: 1.266-1.934) increased risk of outpatients for DMs. Stratification analysis showed that citizens of young ages were susceptive to heat; both genders had a similar relationship between temperature and DMs risk. This study highlights that ambient temperature was associated with DMs outpatients; heat temperature might aggravate DMs risk. The health hazards of heat temperature required more attention, and more effective prevention measurements should be designed and implemented to curb global warming.

摘要

环境温度对皮肤科疾病的影响受到了广泛关注。先前的研究表明,环境温度可能会影响特定的皮肤科疾病,但结果不一致。本研究旨在评估环境温度对中国新乡市皮肤科疾病(DMs)门诊量的短期影响。从 2015 年 1 月 1 日至 2018 年 12 月 31 日,检索了新乡市每日 DMs 门诊量、平均温度、平均相对湿度和空气污染数据。采用分布滞后非线性模型(DLNM)分析环境温度对 DMs 门诊量的影响。我们控制了长期趋势、公共假期、星期几、湿度和空气污染物(NO、PM)等几个潜在的混杂因素。最后,还进行了两项按年龄和性别分层的分析。本研究共纳入 164270 名 DMs 门诊患者,日平均就诊量为 113 人。温度对 DMs 的估计影响是非线性的。热天会使皮肤科疾病的门诊量恶化。以参考中位数温度(17°C)为基准,温度对 DMs 的影响在滞后 0-14 天最为显著;暴露于热天(32°C,第 99 百分位数)与 DMs 门诊量增加 1.565(95%CI:1.266-1.934)的风险相关。分层分析表明,年轻人群对热天敏感;男性和女性之间,温度与 DMs 风险之间存在相似的关系。本研究强调了环境温度与 DMs 门诊量之间的关系;热天可能会加重 DMs 的风险。热天对健康的危害需要引起更多关注,应设计并实施更有效的预防措施,以遏制全球变暖。

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