Department of Obstetrics and Gynecology, University of Alabama, Birmingham, Birmingham, AL, USA.
Department of Obstetrics and Gynecology, Louisiana State University Health, Shreveport, Shreveport, LA, USA.
Adv Ther. 2022 Jul;39(7):3104-3111. doi: 10.1007/s12325-022-02146-w. Epub 2022 May 6.
This study aimed to determine the effect of a prenatal education program for opioid-dependent women on breastfeeding frequency, newborn hospital length of stay, and cost of care for neonates at risk of developing neonatal abstinence syndrome.
From January 1, 2015 to January 1, 2020, opioid-dependent obstetric patients were educated on non-pharmacological preventative measures for neonatal abstinence syndrome (NAS), with focused counseling on breastfeeding. Data were collected and compared to a control group of opioid-dependent pregnant women who received standard care before initiation of the education program.
Sample size calculation revealed that to detect doubling of the breastfeeding rate from 25% to 50% with 80% power and α error of 0.05, 66 participants were required in each group.
There were 75 women with opioid use disorder who had prenatal NAS education (study group) and 108 women with opioid use disorder who underwent standard care before NAS education (control group). Prenatal NAS education participants significantly increased breastfeeding initiation rates compared to the control group. Newborn length of stay significantly decreased after initiation of prenatal NAS education compared to the 36 months before NAS education program.
本研究旨在确定针对阿片类药物依赖女性的产前教育计划对母乳喂养频率、新生儿住院时间和有发生新生儿戒断综合征风险的新生儿护理费用的影响。
2015 年 1 月 1 日至 2020 年 1 月 1 日，对阿片类药物依赖的产科患者进行了针对新生儿戒断综合征（NAS）的非药物预防措施的教育，重点是母乳喂养方面的咨询。收集数据并与接受教育计划启动前标准护理的阿片类药物依赖孕妇对照组进行比较。
样本量计算显示，为了以 80%的功效和 0.05 的α误差检测到母乳喂养率从 25%增加到 50%，每组需要 66 名参与者。
有 75 名患有阿片类药物使用障碍的妇女接受了产前 NAS 教育（研究组），有 108 名患有阿片类药物使用障碍的妇女在接受 NAS 教育前接受了标准护理（对照组）。与对照组相比，产前 NAS 教育参与者显著提高了母乳喂养的起始率。与 NAS 教育计划启动前的 36 个月相比，启动产前 NAS 教育后新生儿住院时间明显缩短。
