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晚期肝病(肾功能不全、肝衰竭、肾上腺功能不全、心肺并发症)的肝代偿失调管理。

Management of Liver Decompensation in Advanced Liver Disease (Renal Impairment, Liver Failure, Adrenal Insufficiency, Cardiopulmonary Complications).

机构信息

Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Insituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Centro de Investigación Biomédica en Red (CIBERehd), Universidad de Alcalá, Ctra. Colmenar Viejo, km 9,100, 28034, Madrid, Spain.

出版信息

Clin Drug Investig. 2022 Jun;42(Suppl 1):15-23. doi: 10.1007/s40261-022-01149-3. Epub 2022 May 6.

Abstract

Systemic complications often occur in patients with advanced liver disease. In particular, the development of renal complications (acute kidney injury, hepatorenal syndrome), acute-on-chronic liver failure, cardiopulmonary diseases, or relative adrenal insufficiency can be serious in patients with advanced liver disease and may determine the patient's quality of life and prognosis. Therefore, the early diagnosis of possible complications is the key to the prompt initiation of specific treatments that can improve quality of life and survival. For this purpose, networking with reference centers where multidisciplinary units are available is essential so that every patient is evaluated in clinical discussions involving specialists from different fields.

摘要

系统性并发症常发生于晚期肝病患者中。特别是,肾脏并发症(急性肾损伤、肝肾综合征)、慢加急性肝衰竭、心肺疾病或相对肾上腺功能不全的发生,在晚期肝病患者中可能较为严重,并可能决定患者的生活质量和预后。因此,早期诊断可能出现的并发症是及时启动特定治疗的关键,这些治疗可以提高生活质量和生存率。为此,与多学科单位的参考中心建立联系至关重要,以便对涉及不同领域专家的临床讨论中的每位患者进行评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7222/9205830/8c3bccaa3ce4/40261_2022_1149_Fig1_HTML.jpg

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