巴西某医院重症监护病房耐碳青霉烯鲍曼不动杆菌的高致死率：一项流行病学监测研究。
High lethality rate of carbapenem-resistant Acinetobacter baumannii in Intensive Care Units of a Brazilian hospital: An epidemiologic surveillance study.
机构信息
Universidade Federal da Grande Dourados, Laboratório de Pesquisa em Ciências da Saúde, Dourados, MS, Brasil.
Stanford University, Division of Infectious Diseases and Geographic Medicine, Stanford, CA, USA.
出版信息
Rev Soc Bras Med Trop. 2022 Apr 29;55:e05292021. doi: 10.1590/0037-8682-0529-2021. eCollection 2022.
BACKGROUND
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a growing threat to public health.
METHODS
A 3-year retrospective study was conducted to evaluate the prevalence and lethality of multidrug-resistant (MDR) A. baumannii isolated from Brazilian patients.
RESULTS
In this study, 219 Acinetobacter baumannii isolates were identified, of which 70.8% (155/219) were isolated from patients hospitalized in intensive care units. Of these, 57.4% (n = 89/155) were assessed, of which 92.1% (82/89) were carbapenem-resistant, and 49 were classified as infected. The lethality rate was 79.6% (39/49).
CONCLUSIONS
We highlight the need of an effective epidemiological surveillance measure to contain the dissemination of CRAB in the hospital environment.
背景
耐碳青霉烯鲍曼不动杆菌（CRAB）对公共卫生构成日益严重的威胁。
方法
进行了一项为期 3 年的回顾性研究，以评估从巴西患者中分离出的耐多药（MDR）鲍曼不动杆菌的流行率和致死率。
结果
在这项研究中，共鉴定出 219 株鲍曼不动杆菌，其中 70.8%（155/219）分离自重症监护病房住院患者。其中，57.4%（n=89/155）进行了评估，其中 92.1%（82/89）为碳青霉烯耐药，49 株为感染。死亡率为 79.6%（39/49）。
结论
我们强调需要采取有效的流行病学监测措施，以遏制医院环境中 CRAB 的传播。
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