BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.
Wiad Lek. 2022;75(3):727-731.
Occlusion of the venous or arterial vessels in childhood is rather rare but dangerous complication. Occurrence of neonatal thrombosis is 0.5 per 10 000 of live newborns. Promoting factors include congenital defects of coagulation, maternal diabetes, neonatal sepsis, necrotic enterocolitis, asphyxia, and metabolic diseases. More than 90 % cases of neonatal thrombosis are associated with catheterization (umbilical arterial or venous, other central venous lines). Acute arterial thrombosis caused by a peripheral venous catheter is very rare complication, but it can result in severe consequences. The article contains a clinical case of right brachial artery thrombosis in a premature boy with extremely low body weight complicated by development of dry gangrene and amputation of the limb. Complex risk factors promoting development of neonatal arterial thrombosis were found: preterm birth, neonatal sepsis, possible incorrect insertion of a peripheral venous catheter. Associative factors were congenital developmental defects of the intestine (high rectal atresia) and heart (bicuspid aortal valve, open oval foramen), and maternal factors. The authors emphasize their attention on the necessity to continuous education of the medical staff concerning the technique of catheter insertion and care of them, absolute implementation of safety policy concerning nosocomial infection, adequate provision of ultrasound examination devices with high rarefaction sensors, involvement of a multi-disciplinary team of specialists to manage complicated clinical cases.
儿童时期静脉或动脉血管闭塞是一种罕见但危险的并发症。新生儿血栓形成的发生率为每 10 000 例活产儿中有 0.5 例。促发因素包括先天性凝血缺陷、母体糖尿病、新生儿败血症、坏死性小肠结肠炎、窒息和代谢疾病。超过 90%的新生儿血栓与导管插入术(脐动脉或静脉、其他中心静脉导管)有关。由外周静脉导管引起的急性动脉血栓形成是一种非常罕见的并发症,但可导致严重后果。本文包含一例极低出生体重早产儿右肱动脉血栓形成的临床病例,该患儿并发干性坏疽,肢体截肢。发现了促进新生儿动脉血栓形成的复杂危险因素:早产、新生儿败血症、可能不正确插入外周静脉导管。关联因素包括先天性肠发育缺陷(高位直肠闭锁)和心脏(二叶主动脉瓣、卵圆孔未闭)以及母体因素。作者强调,有必要对医务人员进行导管插入技术和护理的持续教育,绝对执行医院感染安全政策,充分提供具有高稀疏传感器的超声检查设备,让多学科专家团队参与管理复杂的临床病例。