Barry University.
University of Mississippi.
Res Q Exerc Sport. 2023 Sep;94(3):812-825. doi: 10.1080/02701367.2022.2057401. Epub 2022 May 6.
Heart rate variability (HRV) has gained acceptance as a key marker of cardiovascular health. We compared HRV responses after continuous moderate-intensity exercise (CMIE) and high-intensity interval exercise (HIIE) matched for intensity and duration in individuals with midspectrum chronic kidney disease (CKD). Twenty men and women (age 62.0 ± 10 yrs.) diagnosed with CKD stages G3a and G3b participated in a 2 (condition) x 4 (time point) repeated cross-over measures design study. HRV time-domain indices were based on the standard deviation of all NN intervals (SDNN) and the square root of the mean of the sum of the squares of differences between adjacent NN intervals (RMSSD) and frequency domain. High-frequency (HF), low-frequency (LF), total power (TP) were examined. CMIE consisted of treadmill walking for 30 minutes at a 2% incline and speed corresponding to 60%-65% of reserve volume of oxygen (VOR). HIIE included five intervals of 3 minutes at 90% of VOR and 2 minutes at 20% VOR intervals. Conditions were designed to be of the same average intensity (60% to 65% of VOR) and caloric expenditure (~144 kcal). Immediately following exercise SDNN, RMSSD, HF, LF, and TP were significantly lower compared to before exercise ( <.05). HRV responses were not different between conditions and conditions X time ( >.05). Thirty minutes of either CMIE or HIIE decreased HRV indices, pointing to an autonomic imbalance favoring vagal mediation. HRV's responses regarding HIIE were no different from CMIE, therefore, from an autonomic function point of view this similarity may be useful for CKD exercise prescription and programming.
心率变异性（HRV）已被接受为心血管健康的关键标志物。我们比较了中谱慢性肾脏病（CKD）患者在强度和持续时间匹配的连续中等强度运动（CMIE）和高强度间歇运动（HIIE）后的 HRV 反应。20 名年龄为 62.0 ± 10 岁的男性和女性被诊断为 CKD 第 3a 和 3b 期，参加了一项 2（条件）x4（时间点）重复交叉测量设计研究。HRV 时域指数基于所有 NN 间隔的标准差（SDNN）和均方根的平均值的平方和之间的差异之间的相邻 NN 间隔（RMSSD）和频域。高频（HF）、低频（LF）、总功率（TP）进行了检查。CMIE 由在 2%倾斜度和速度的跑步机行走 30 分钟组成，该速度对应于储备氧体积（VOR）的 60%-65%。HIIE 包括 5 个 3 分钟间隔，VOR 为 90%，VOR 间隔为 2 分钟。条件设计为相同的平均强度（VOR 的 60%至 65%）和热量消耗（~144 卡路里）。运动后即刻，SDNN、RMSSD、HF、LF 和 TP 与运动前相比显著降低（<0.05）。条件之间和条件 x 时间之间的 HRV 反应没有差异（>0.05）。30 分钟的 CMIE 或 HIIE 均降低了 HRV 指数，表明自主神经失衡有利于迷走神经介导。HIIE 的 HRV 反应与 CMIE 没有不同，因此，从自主功能的角度来看，这种相似性可能对 CKD 运动处方和编程有用。
