详细超声作为颅脊柱异常的筛查方法。

Detailed ultrasound as a screening method for craniospinal abnormalities.

作者信息

Greco P, Gargano G, Carriero C, Clericò L, Diaferia A, Mele G, Loizzi P

出版信息

Clin Exp Obstet Gynecol. 1987;14(2):115-8.

Abstract

High resolution diagnostic ultrasound was assessed as a screening method for craniospinal anomalies during the second trimester of pregnancy in a population at low risk for neural tube defects (83,403 mothers). The effectiveness of the test was about 60% and the failure rate mainly due to late attendance. In a subgroup (9325) where the screening purposes were satisfactorily fulfilled, the detection rate (87%) was substantially greater. The significance of the results and the cost/benefit ratio, especially compared with serum alpha-feto protein screening services, are then discussed.

摘要

在神经管缺陷低风险人群（83403名母亲）中，高分辨率诊断超声被评估为妊娠中期筛查颅脊柱异常的一种方法。该检测的有效性约为60%，失败率主要归因于就诊过晚。在一个筛查目的得到满意实现的亚组（9325人）中，检测率（87%）要高得多。随后讨论了这些结果的意义以及成本效益比，特别是与血清甲胎蛋白筛查服务相比。