Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK
Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.
BMJ Case Rep. 2022 May 6;15(5):e248872. doi: 10.1136/bcr-2022-248872.
A woman in her 20s presented with progressive weakness of her left arm and leg, slurred speech and swallowing difficulties. The clinical presentation and neurophysiological tests were consistent with motor neuron disease. She was referred to the regional ventilation unit for respiratory muscle function testing. This confirmed restrictive spirometry and borderline sniff nasal inspiratory pressure and cough peak expiratory flow. Three years later, she presented with an unplanned pregnancy and expressed the wish to continue the pregnancy to term. She was monitored throughout pregnancy with interval respiratory muscle testing and was reviewed in the high-risk pregnancy anaesthetic clinic. She was also closely monitored by the obstetrics and gynaecology team. A multidisciplinary team meeting between all stakeholders agreed on caesarean section delivery at 34 weeks. The pregnancy and the delivery were without complications; the baby was healthy and both mother and baby remain well to date.
一位 20 多岁的女性出现左侧手臂和腿部进行性无力、言语含糊和吞咽困难。临床表现和神经生理学检查符合运动神经元病。她被转介到区域通气单位进行呼吸肌功能测试。这证实了限制性肺量测定和边界嗅探鼻吸气压力和咳嗽呼气峰流速。三年后，她出现了一次意外怀孕，并表示希望继续妊娠至足月。在整个怀孕期间，她一直接受呼吸肌测试，并在高危妊娠麻醉诊所接受了检查。妇产科团队也对她进行了密切监测。所有利益相关者之间的多学科团队会议一致同意在 34 周行剖宫产术。妊娠和分娩均无并发症；婴儿健康，母婴状况良好。
