Department of Neurosurgery, Johns Hopkins Hospital, 600 N. Wolfe St, Meyer 7-113, Baltimore, 21287, MD, USA.
Department of Orthopedic Surgery, Johns Hopkins Hospital, 600 N. Wolfe St, Meyer 7-113, Baltimore, 21287, MD, USA.
Spine J. 2022 Oct;22(10):1601-1609. doi: 10.1016/j.spinee.2022.04.012. Epub 2022 May 4.
Awake spine surgery is growing in popularity, and may facilitate earlier postoperative recovery, reduced cost, and fewer complications than spine surgery conducted under general anesthesia (GA). However, trends in the adoption of awake (ie, non-GA) spine surgery have not been previously studied.
To investigate temporal trends in non-GA spine surgery utilization and outcomes in the United States.
STUDY DESIGN/SETTING: A retrospective observational study.
Patients undergoing cervical or lumbar decompression or/and fusion from the American College of Surgeons National Surgical Quality Improvement Program database records dated 2005-2019.
The primary outcome was the adoption trends of awake cervical and lumbar spine operations from 2005 to 2019. The secondary outcomes included the outcomes trends of 30-day complications, readmission rates, and length of stay in cervical and lumbar spine operations from 2005 to 2019.
Patients were stratified into two groups: GA and non-GA (regional, epidural, spinal, monitored anesthesia care/intravenous sedation). Pearson chi-square or Fisher exact test and independent-sample t test were used to compare demographics between groups. Jonckheere-Terpstra test was used to determine whether trends and outcomes of non-GA operations from 2005 to 2019 were statistically significant. No non-GA spine operations were reported in the database from 2005 to 2006.
We included 301,521 patients who underwent cervical or lumbar spine operations from 2005 to 2019. GA was used in 294,903 (97.8%) operations; 6,618 (2.2%) operations were non-GA. Patients in the non-GA cohort were more likely to be younger (50.1 vs 57.2 years; p<.001), less likely to have American Society of Anesthesiologists classification ≥3 (39.7% vs 48.3%; p<.001), and to have lower BMI (27.8 vs 31.5 kg/m; p<.001), outpatient admission status (10.8% vs 4.0%; p<.001), and fewer bleeding disorders (0.0% vs 1.2%; p<.001). The proportion of non-GA spine operations increased from nearly 0% in 2005 to 2.1% in 2019. The increase in non-GA operations was statistically significant in cervical (0.0%-1.1%) and lumbar (0.0%-2.9%) operations. For non-GA lumbar operations performed 2007-2019, 30-day complication rates, readmission rates, and mean length of stay all decreased (19.1%-5.4%, p<.05; 5.9%-2.8%, p<.05; 30.9 hours-24.9 hours, p<.05, respectively). Similarly, for non-GA cervical operations performed 2007-2019, 30-day complication rates, readmission rates, and mean length of stay all decreased (20.1%-6.1%, p<.05; 6.7%-3.7%, p<.05; 27.0-20.0 hours p<.05, respectively).
Our trends analysis revealed increasing utilization and improved outcomes of non-GA spine surgery from 2005 to 2019; however, the proportion of non-GA spine operations remains small. Future research should investigate the barriers to adoption of non-GA spine surgery.
唤醒脊柱手术越来越受欢迎,与全身麻醉(GA)下进行的脊柱手术相比,它可能更早地促进术后恢复,降低成本,减少并发症。然而,以前尚未研究过非 GA 脊柱手术采用的趋势。
调查美国非 GA 脊柱手术利用和结果的时间趋势。
研究设计/设置:回顾性观察性研究。
从美国外科医师学会国家手术质量改进计划数据库记录(2005-2019 年)中选择接受颈椎或腰椎减压或融合的患者。
2005 年至 2019 年期间,唤醒颈椎和腰椎手术的采用趋势。次要结局包括 2005 年至 2019 年期间 30 天并发症、再入院率和颈椎和腰椎手术住院时间的结局趋势。
患者分为两组:GA 和非 GA(区域、硬膜外、脊髓、监测麻醉护理/静脉镇静)。使用 Pearson 卡方或 Fisher 确切检验和独立样本 t 检验比较组间的人口统计学特征。Jonckheere-Terpstra 检验用于确定 2005 年至 2019 年非 GA 手术的趋势和结果是否具有统计学意义。2005 年至 2006 年数据库中未报告非 GA 脊柱手术。
我们纳入了 2005 年至 2019 年接受颈椎或腰椎手术的 301,521 名患者。GA 用于 294,903 例(97.8%)手术;6,618 例(2.2%)手术为非 GA。非 GA 组的患者更年轻(50.1 岁比 57.2 岁;p<.001),不太可能有美国麻醉医师协会分类≥3(39.7%比 48.3%;p<.001),BMI 较低(27.8 千克/米比 31.5 千克/米;p<.001),门诊入院状态(10.8%比 4.0%;p<.001),出血性疾病较少(0.0%比 1.2%;p<.001)。非 GA 脊柱手术的比例从 2005 年的近 0%增加到 2019 年的 2.1%。颈椎(0.0%-1.1%)和腰椎(0.0%-2.9%)手术中非 GA 手术的增加具有统计学意义。对于 2007 年至 2019 年进行的非 GA 腰椎手术,30 天并发症发生率、再入院率和平均住院时间均降低(19.1%-5.4%,p<.05;5.9%-2.8%,p<.05;30.9 小时-24.9 小时,p<.05)。同样,对于 2007 年至 2019 年进行的非 GA 颈椎手术,30 天并发症发生率、再入院率和平均住院时间均降低(20.1%-6.1%,p<.05;6.7%-3.7%,p<.05;27.0-20.0 小时,p<.05)。
我们的趋势分析显示,从 2005 年到 2019 年,非 GA 脊柱手术的利用和结果都有所改善;然而,非 GA 脊柱手术的比例仍然很小。未来的研究应调查非 GA 脊柱手术采用的障碍。