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未能检测到胰岛素低血糖对正常受试者血清甲状旁腺激素和钙的急性影响。

Failure to detect acute effects of insulin hypoglycemia on serum PTH and calcium in normal subjects.

作者信息

Broulík P D, Pacovský V, Masek Z, Kopecká J

出版信息

Endocrinol Exp. 1987 Mar;21(1):65-9.

PMID:3552620
Abstract

The effect of insulin induced hypoglycemic stress on parathyroid hormone serum level in man were evaluated. Porcine crystalline insulin (0.2 U kg-1 i.v.) caused symptomatic hypoglycemia and increase of adrenaline level in serum in all subjects. In the present study we could not detect any significant effects of insulin and of insulin induced hypoglycemia on serum parathormone and calcium levels, though such hypoglycemia is a potent stimulus to endogenous catecholamine secretion. The results support the view that the adrenergic system does not play any major role in regulating the secretion of parathormone which is contrasting to some findings reported by others.

摘要

评估了胰岛素诱导的低血糖应激对人体甲状旁腺激素血清水平的影响。猪结晶胰岛素(0.2 U/kg静脉注射)在所有受试者中均引起症状性低血糖并使血清肾上腺素水平升高。在本研究中,尽管这种低血糖是内源性儿茶酚胺分泌的有效刺激,但我们未检测到胰岛素及胰岛素诱导的低血糖对血清甲状旁腺激素和钙水平有任何显著影响。这些结果支持了这样一种观点,即肾上腺素能系统在调节甲状旁腺激素分泌方面不发挥任何主要作用,这与其他一些人报道的某些发现形成对比。

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Failure to detect acute effects of insulin hypoglycemia on serum PTH and calcium in normal subjects.未能检测到胰岛素低血糖对正常受试者血清甲状旁腺激素和钙的急性影响。
Endocrinol Exp. 1987 Mar;21(1):65-9.
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Insulin-induced hypoglycaemia stimulates secretion of parathyroid hormone.胰岛素诱导的低血糖会刺激甲状旁腺激素的分泌。
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