Furuse Yuki
Institute for Frontier Life and Medical Sciences, Kyoto University.
Hakubi Center for Advanced Research, Kyoto University.
Uirusu. 2021;71(1):11-18. doi: 10.2222/jsv.71.11.
A variety of viral hemorrhagic fevers such as Ebola virus disease exist in Africa and impose a great threat in public health due to their high fatality. It is considered to be difficult to eradicate the etiological agents of viral hemorrhagic fever because they have non-human natural hosts. Therefore, the importance of public health measures remains high in addition to the urgent need for the development of medicines for treatment and prevention. Furthermore, public health measures directly lead to the accumulation of epidemiological knowledge about the diseases. As an infectious disease consultant for the World Health Organization, I have been involved with public health activities including the development of clinical guidelines, the establishment of laboratory diagnostic systems, the training for infection, prevention and control, the planning of budget for outbreak response, and the analysis of epidemiological data. On the last point, I reported the situation of Ebola virus disease outbreak in Liberia, 2014-2015 and Lassa fever outbreak in Nigeria, 2018-2019 describing the risk factors, morbidity, and mortality of the diseases.
非洲存在多种病毒性出血热,如埃博拉病毒病,因其高致死率对公共卫生构成巨大威胁。由于病毒性出血热的病原体有非人类自然宿主,所以根除这些病原体被认为很困难。因此,除了迫切需要开发治疗和预防药物外,公共卫生措施的重要性依然很高。此外,公共卫生措施直接有助于积累有关这些疾病的流行病学知识。作为世界卫生组织的传染病顾问,我参与了公共卫生活动,包括制定临床指南、建立实验室诊断系统、进行感染预防与控制培训、规划疫情应对预算以及分析流行病学数据。关于最后一点,我报告了2014 - 2015年利比里亚埃博拉病毒病疫情以及2018 - 2019年尼日利亚拉沙热疫情的情况,描述了这些疾病的风险因素、发病率和死亡率。