新冠病毒病后侵袭性肾和胃肠道毛霉菌病。

Post coronavirus disease- 19 invasive renal and gastrointestinal mucormycosis.

机构信息

Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, India.

出版信息

Indian J Med Microbiol. 2022 Jul-Sep;40(3):462-464. doi: 10.1016/j.ijmmb.2022.03.006. Epub 2022 May 6.

DOI:10.1016/j.ijmmb.2022.03.006

PMID:35527119

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9072856/

Abstract

A 68-year-old female patient who was treated with anti-viral, steroids and biologics for coronavirus disease- 19 (COVID- 19) infection presented to our facility following right abdominal and flank pain since a week. Initially attributed to pancreatitis and right sided pyelonephritis, it was diagnosed as mucormycosis on KOH mount following CT-guided renal biopsy. She underwent right total nephrectomy and Whipple's surgery followed by Isavuconazole and liposomal Amphotericin B. This is a rare presentation of renal and gastrointestinal mucormycosis in a patient without diabetes mellitus following COVID- 19 infection. High suspicion and early diagnosis help in timely treatment of this life-threatening infection.

摘要

一位 68 岁的女性患者因 COVID-19 感染接受了抗病毒、类固醇和生物制剂治疗，一周来出现右腹部和侧腰痛，来我院就诊。最初归因于胰腺炎和右侧肾盂肾炎，在 CT 引导下肾活检后，KOH 载片检查诊断为毛霉菌病。她随后接受了右肾全切术和 Whipple 手术，接着使用伊曲康唑和脂质体两性霉素 B 治疗。这是一例 COVID-19 感染后无糖尿病患者的肾脏和胃肠道毛霉菌病的罕见表现。高度怀疑和早期诊断有助于及时治疗这种危及生命的感染。