激肽释放酶-激肽系统各组分对体外精子活力的温度依赖性影响。

Temperature-dependent effects of the components of kallikrein-kinin system on sperm motility in vitro.

作者信息

Sato H, Schill W B

出版信息

Fertil Steril. 1987 Apr;47(4):684-8. doi: 10.1016/s0015-0282(16)59122-5.

Abstract

The effect of kallikrein and bradykinin on sperm motility was studied. For investigation of whether the effect is not temperature dependent, sperm motility and velocity were measured after incubation with kallikrein or bradykinin at different temperatures. The effect of kallikrein on sperm motility and velocity was demonstrated significantly at 22 degrees C. At 37 degrees C, this effect was absent, but with captopril the effect of kallikrein on sperm velocity was observed. Bradykinin stimulated sperm motility and velocity at 22 degrees C and at 33 degrees C. However, it did not stimulate sperm motility at 37 degrees C. With 1.10 phenantroline, the effect of bradykinin on sperm motility was detected. These results indicate that kallikrein and bradykinin stimulate sperm motility and velocity and that their effects are strongly temperature dependent.

摘要

研究了激肽释放酶和缓激肽对精子活力的影响。为了研究这种影响是否与温度无关，在不同温度下用激肽释放酶或缓激肽孵育后测量精子活力和速度。在22摄氏度时，激肽释放酶对精子活力和速度的影响显著。在37摄氏度时，这种影响不存在，但使用卡托普利时，可观察到激肽释放酶对精子速度的影响。缓激肽在22摄氏度和33摄氏度时刺激精子活力和速度。然而，它在37摄氏度时不刺激精子活力。使用1,10-菲啰啉时，可检测到缓激肽对精子活力的影响。这些结果表明，激肽释放酶和缓激肽刺激精子活力和速度，且它们的作用强烈依赖于温度。