Wisser J, Knitza R, Schmid-Tannwald I, Strowitzki T, Nerlich A, Hepp H
Geburtshilfe Frauenheilkd. 1987 Jan;47(1):8-14. doi: 10.1055/s-2008-1035764.
Between October 1st 1983 and January 31st 1986 we diagnosed various anomalies on 116 foetuses at the Department of Obstetrics and Gynaecology, Klinikum Grosshadern, Munich. In 103 cases we made a correct diagnosis. This group of patients included 45 non-viable foetuses. Severe anomalies of the foetal central nervous system and lethal dwarfism were diagnosed correctly. On the other hand, antenatal diagnosis of bilateral nonfunctional kidneys and non-correctable cardiac malformations poses problems. We feel that in the case of a definitive prenatal diagnosis of an anomaly for which there is no known medical treatment and which is not compatible with life, the decision as to further procedure should be made at this stage. Before 24 weeks gestation, termination of pregnancy on foetal grounds should be discussed with the parents. Thereafter, preterm labour is preferable to the dangers of obstructed labour at term and should be conducted without foetal monitoring.
1983年10月1日至1986年1月31日期间,我们在慕尼黑格罗斯哈登临床医院妇产科对116例胎儿诊断出各种异常情况。其中103例诊断正确。这组患者包括45例无法存活的胎儿。胎儿中枢神经系统的严重异常和致死性侏儒症均被正确诊断。另一方面,产前诊断双侧无功能肾和无法矫正的心脏畸形存在问题。我们认为,对于无法进行医学治疗且与生命不相容的异常情况,如果进行了明确的产前诊断,应在此时做出进一步处理的决定。妊娠24周前,应与父母讨论基于胎儿原因终止妊娠的问题。此后,早产比足月分娩梗阻的危险更可取,且应在不进行胎儿监测的情况下进行。