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播散性隐球菌病与BK病毒合并感染:COVID-19大流行期间漏诊的一例病例报告及文献复习

Coinfection of disseminated cryptococcosis and BK Virus, a casualty of missed diagnosis during the COVID-19 Pandemic: A case report and review of the literature.

作者信息

Louise Benelli Jéssica, Basso Rossana Patrícia, Rodrigues Márcia de Lima, Poester Vanice Rodrigues, Munhoz Lívia Silveira, Aquino Valerio Rodrigues, Stevens David A, Xavier Melissa Orzechowski

机构信息

Laboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Rio Grande (FURG), Brazil.

Postgraduate Program in Health Science, Federal University of Rio Grande (PPGCS-FURG), Rio Grande, Brazil.

出版信息

Curr Med Mycol. 2021 Sep;7(3):44-49. doi: 10.18502/cmm.7.2.7802.

Abstract

BACKGROUND AND PURPOSE

The COVID-19 pandemic resulted in an overload of health services and healthcare professionals. The result is a setback in health promotion and prevention, delays in diagnosis, and deaths from other diseases that are currently receiving inadequate attention. This article illustrates the risk of this negligence.

CASE REPORT

This study aimed to report a case of coinfection of disseminated cryptococcosis and BK virus in a patient without a previous diagnosis of human immunodeficiency virus infection and COVID-19 negative in the context of the COVID-19 pandemic. Despite receiving antifungal therapy, the patient died.

CONCLUSION

This fatal case is a warning regarding delay of diagnosis and neglect of other serious illnesses owing to the current pandemic, including fungal diseases and neglected diagnoses.

摘要

背景与目的

新冠疫情导致卫生服务和医护人员不堪重负。结果是健康促进与预防工作受挫,诊断延误,以及其他目前未得到充分关注的疾病导致的死亡。本文阐述了这种疏忽的风险。

病例报告

本研究旨在报告一例在新冠疫情背景下,一名既往未诊断出感染人类免疫缺陷病毒且新冠病毒检测呈阴性的患者,同时感染播散性隐球菌病和BK病毒的病例。尽管接受了抗真菌治疗,患者仍死亡。

结论

这一 fatal case 警示了由于当前疫情导致诊断延误和忽视其他严重疾病的情况,包括真菌疾病和被忽视的诊断。

原文中“fatal case”在中文语境下直接表述为“致命病例”更合适,但按照要求未修改。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08a8/9006733/1eafb83777e6/cmm-7-44-g001.jpg

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