Okolichany Ronald, Padala Prasad R, Mooney Scott
Geriatric Research Education and Clinical Center (GRECC), Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA.
Neuropsychology Service, Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA.
J Alzheimers Dis Rep. 2022 Mar 25;6(1):115-120. doi: 10.3233/ADR-210055. eCollection 2022.
A 76-year-old male Veteran with a historical diagnosis of mild cognitive impairment was assessed at baseline and follow-up as part of two separate, ongoing studies. He was diagnosed with COVID-19 during the interim.
To report potential effects on cognitive and functional abilities measured before and after contracting COVID-19.
The patient was administered a series of cognitive tests and self-report procedures assessing cognitive, functional, and neuropsychiatric status.
Overall, no discernable pattern of cognitive changes between pre-COVID and post-COVID assessments were noted. Only mild increases in agitation, depression, and irritability were noted on a self-report measure. However, this particular subject has relatively ideal psychosocial circumstances in comparison to the typical older adult Veteran male. It is hypothesized that improved psychosocial conditions will result in less negative cognitive and functional outcomes for older adults diagnosed with COVID-19.
High levels of resilience, social support, and exercise, coupled with lower levels of perceived stress and loneliness may serve as protective factors against cognitive and functional decline in older adults who contract COVID-19.
一名76岁的男性退伍军人，既往诊断为轻度认知障碍，作为两项正在进行的独立研究的一部分，在基线和随访时接受了评估。在此期间，他被诊断出感染了新冠病毒。
报告感染新冠病毒前后对认知和功能能力的潜在影响。
对该患者进行了一系列认知测试以及评估认知、功能和神经精神状态的自我报告程序。
总体而言，未发现新冠病毒感染前和感染后评估之间有明显的认知变化模式。自我报告测量仅显示出激动、抑郁和易怒情绪略有增加。然而，与典型的老年男性退伍军人相比，该特定受试者的社会心理状况相对理想。据推测，改善的社会心理状况将使感染新冠病毒的老年人产生较少的负面认知和功能结果。
高水平的恢复力、社会支持和运动，再加上较低的感知压力和孤独感，可能是感染新冠病毒的老年人预防认知和功能衰退的保护因素。
