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一例通过全基因组测序发现与加勒比地区暴露相关的真菌性动脉瘤病例。

A Case of Mycotic Aneurysm Linked to Exposure in the Caribbean via Whole-Genome Sequencing.

作者信息

Speiser Lisa J, Kasule Sabirah, Hall Carina M, Sahl Jason W, Wagner David M, Saling Chris, Kole Amy, Meltzer Andrew J, Davila Victor, Orenstein Robert, Grys Thomas, Graf Erin

机构信息

Mayo Clinic Arizona, Phoenix, Arizona, USA.

Northern Arizona University, Flagstaff, Arizona, USA.

出版信息

Open Forum Infect Dis. 2022 Mar 21;9(5):ofac136. doi: 10.1093/ofid/ofac136. eCollection 2022 May.

DOI:10.1093/ofid/ofac136
PMID:35531377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9070330/
Abstract

Melioidosis, an infection caused by , has a very high risk of mortality when treated, with an even higher risk of fatality if undiagnosed or not treated appropriately. It is endemic to Asia, Australia, South America, and the Caribbean; however, the number of melioidosis cases reported in the United States has been increasing. Therefore, physicians should be aware of this clinical entity and its possible presentations. Mycotic aneurysms due to are extremely rare, accounting for ~1%-2% of cases. Here we describe a rare case of melioidosis presenting as a mycotic aneurysm in the United States, highlight the potential for diagnostic challenges and epidemiologic concerns, and provide a review of mycotic aneurysm cases due to published to date.

摘要

类鼻疽是由[病原体名称未给出]引起的一种感染,治疗时死亡率很高,如果未被诊断或未得到适当治疗,死亡风险更高。它在亚洲、澳大利亚、南美洲和加勒比地区为地方病;然而,美国报告的类鼻疽病例数量一直在增加。因此,医生应该了解这种临床病症及其可能的表现。由[病原体名称未给出]引起的真菌性动脉瘤极其罕见,约占病例的1%-2%。在此,我们描述了美国一例罕见的以真菌性动脉瘤形式出现的类鼻疽病例,强调了诊断挑战的可能性和流行病学问题,并对迄今为止已发表的由[病原体名称未给出]引起的真菌性动脉瘤病例进行了综述。

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本文引用的文献

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The Darwin Prospective Melioidosis Study: a 30-year prospective, observational investigation.达尔文前瞻性类鼻疽病研究:一项 30 年的前瞻性观察性研究。
Lancet Infect Dis. 2021 Dec;21(12):1737-1746. doi: 10.1016/S1473-3099(21)00022-0. Epub 2021 Jul 22.
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Aortic endograft infection secondary to : A case report and review of the literature.继发于主动脉腔内移植物的感染:一例病例报告及文献综述
J Vasc Surg Cases Innov Tech. 2021 May 21;7(3):421-424. doi: 10.1016/j.jvscit.2021.04.023. eCollection 2021 Sep.
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Mycotic aneurysm secondary to melioidosis in China: A series of eight cases and a review of literature.
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PLoS Negl Trop Dis. 2020 Aug 12;14(8):e0008525. doi: 10.1371/journal.pntd.0008525. eCollection 2020 Aug.
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Unusual presentation of melioidosis in a returning traveler.一名归国旅行者中类鼻疽的不寻常表现。
IDCases. 2020 May 12;20:e00809. doi: 10.1016/j.idcr.2020.e00809. eCollection 2020.
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Melioidosis in a Resident of Texas with No Recent Travel History, United States.美国德克萨斯州一位近期无旅行史居民感染类鼻疽,
Emerg Infect Dis. 2020 Jun;26(6):1295-1299. doi: 10.3201/eid2606.190975.
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Burkholderia pseudomallei was Identified in a Melioidosis Aneurysm using Polymerase Chain Reaction Targeting 23S rRNA.
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Infected aneurysm after returning from Southeast Asia: think !从东南亚回来后出现感染性动脉瘤:要警惕!
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Melioidosis.类鼻疽病。
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