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大型学术医疗中心免疫功能低下宿主革兰阴性血流感染的随访血培养实践

Follow-up Blood Culture Practices for Gram-Negative Bloodstream Infections in Immunocompromised Hosts at a Large Academic Medical Center.

作者信息

Buzzalino Lauren Groft, Mease James, Bernhardi Ciera L, Bork Jacqueline T, Johnson J Kristie, Claeys Kimberly C

机构信息

The Johns Hopkins Hospital, Baltimore, Maryland, USA.

Food and Drug Administration, Silver Spring, Maryland, USA.

出版信息

Open Forum Infect Dis. 2022 Apr 15;9(5):ofac173. doi: 10.1093/ofid/ofac173. eCollection 2022 May.

DOI:10.1093/ofid/ofac173
PMID:35531383
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9070332/
Abstract

The role of follow-up blood cultures (FUBCs) in gram-negative bloodstream infections to improve clinical outcomes remains controversial, especially among immunocompromised patients. Among 139 patients, FUBCs were common (117, 84.2%); however, positive FUBCs were rare (3, 2.6%). Only presence of fever was associated with a positive FUBC.

摘要

在革兰氏阴性菌血流感染中,后续血培养(FUBCs)对改善临床结局的作用仍存在争议,尤其是在免疫功能低下的患者中。在139例患者中,FUBCs很常见(117例,84.2%);然而,FUBCs呈阳性的情况很少见(3例,2.6%)。只有发热与FUBCs阳性相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1462/9070332/ee64a56aafba/ofac173_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1462/9070332/ee64a56aafba/ofac173_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1462/9070332/ee64a56aafba/ofac173_fig1.jpg

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Open Forum Infect Dis. 2021 Oct 11;8(10):ofab434. doi: 10.1093/ofid/ofab434. eCollection 2021 Oct.
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Blood Culture Utilization in the Hospital Setting: a Call for Diagnostic Stewardship.血培养在医院环境中的应用:呼吁采取诊断管理措施。
J Clin Microbiol. 2022 Mar 16;60(3):e0100521. doi: 10.1128/JCM.01005-21. Epub 2021 Jul 14.
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Incidence and utility of follow-up blood cultures in cancer patients with gram-negative bacteremia.
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Infect Drug Resist. 2024 May 9;17:1811-1825. doi: 10.2147/IDR.S460744. eCollection 2024.
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Risk factors for positive follow-up blood cultures in Gram-negative bacteremia among immunocompromised patients with neutropenia.中性粒细胞减少的免疫功能低下患者革兰阴性菌血症随访血培养阳性的危险因素。
Transpl Infect Dis. 2024 Feb;26(1):e14203. doi: 10.1111/tid.14203. Epub 2023 Nov 27.
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