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巨大左房黏液瘤间接导致二尖瓣反流:一例报告

Mitral regurgitation indirectly caused by giant left atrial myxoma: a case report.

作者信息

Nagatomi Shuji, Matsumoto Kazuhisa, Tateishi Naoki, Toyokawa Kenji, Mukaihara Kosuke, Soga Yoshiharu

机构信息

Department of Cardiovascular Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

出版信息

J Surg Case Rep. 2022 May 5;2022(5):rjac208. doi: 10.1093/jscr/rjac208. eCollection 2022 May.

DOI:10.1093/jscr/rjac208
PMID:35531437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9072002/
Abstract

Cardiac myxoma is a benign primary cardiac tumor. Herein, we report a case of mitral regurgitation due to annular dilatation caused by giant left atrial myxoma. The transthoracic echocardiogram performed in a 65-year-old man who suffered from worsening exertional dyspnea detected a large mass of 81 × 31 mm in the left atrium, causing functional severe mitral stenosis. Radical mass resection was performed. After removal of the aortic clamp, an intraoperative transesophageal echocardiogram revealed moderate mitral regurgitation due to annulus dilatation. Mitral annuloplasty was performed, and mitral regurgitation was controlled. The mass was diagnosed as myxoma histologically. A large myxoma that affects mitral annulus dilatation is rarely reported. Mitral regurgitation may be masked by the presence of a large myxoma. Therefore, it should be carefully evaluated after resection, and mitral annuloplasty should be considered in the presence of significant mitral regurgitation due to mechanical annulus dilatation caused by myxoma.

摘要

心脏黏液瘤是一种原发性心脏良性肿瘤。在此,我们报告一例因巨大左心房黏液瘤导致瓣环扩张引起二尖瓣反流的病例。一名65岁男性因劳力性呼吸困难加重接受经胸超声心动图检查,发现左心房有一个81×31mm的大肿块,导致功能性严重二尖瓣狭窄。进行了根治性肿块切除术。移除主动脉夹后,术中经食管超声心动图显示由于瓣环扩张导致中度二尖瓣反流。进行了二尖瓣瓣环成形术,二尖瓣反流得到控制。该肿块经组织学诊断为黏液瘤。影响二尖瓣瓣环扩张的大黏液瘤鲜有报道。大黏液瘤的存在可能掩盖二尖瓣反流。因此,切除后应仔细评估,对于因黏液瘤导致机械性瓣环扩张引起的显著二尖瓣反流,应考虑进行二尖瓣瓣环成形术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/72b8ebf46eb4/rjac208f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/c0909e304a50/rjac208f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/49171fe0f97e/rjac208f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/df12261a93ef/rjac208f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/72b8ebf46eb4/rjac208f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/c0909e304a50/rjac208f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/49171fe0f97e/rjac208f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/df12261a93ef/rjac208f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a1/9072002/72b8ebf46eb4/rjac208f4.jpg

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本文引用的文献

1
Mitral valve myxoma presenting with transient ischemic attack: a case report and review of the literature.二尖瓣黏液瘤伴短暂性脑缺血发作:一例报告并文献复习
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Mitral valve regurgitation due to annular dilatation caused by a huge and floating left atrial myxoma.巨大漂浮性左房黏液瘤致瓣环扩张引起的二尖瓣反流
Kardiochir Torakochirurgia Pol. 2015 Sep;12(3):248-50. doi: 10.5114/kitp.2015.54463. Epub 2015 Sep 28.
3
Mitral valve annular dilatation caused by left atrial myxoma.
左心房黏液瘤导致二尖瓣环扩张。
Heart Lung Circ. 2009 Apr;18(2):145-7. doi: 10.1016/j.hlc.2007.10.017. Epub 2008 Jan 31.
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Cardiac myxomas.心脏黏液瘤
N Engl J Med. 1995 Dec 14;333(24):1610-7. doi: 10.1056/NEJM199512143332407.
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Cardiac myxomas: a clinicopathologic profile.心脏黏液瘤:临床病理特征
Am J Pathol. 1980 Oct;101(1):219-40.
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Deoxyribonucleic acid ploidy pattern of cardiac myxomas. Another predictor of biologically unusual myxomas.心脏黏液瘤的脱氧核糖核酸倍体模式。生物学上异常黏液瘤的另一个预测指标。
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