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卡泊三醇/倍他米松二丙酸酯泡沫组合的短期和长期疗效

Short Term and Long-Term Efficacy of Calcipotriene/ Betamethasone Dipropionate Foam Combination.

作者信息

Jalili Ahmad, Bewley Anthony, Sticherling Michael, Stein Gold Linda

机构信息

Dermatology & Skin Care Clinic, Buochs, Switzerland.

Barts Health NHS Trust and Queen Mary University London, London, UK.

出版信息

Clin Cosmet Investig Dermatol. 2022 May 2;15:809-814. doi: 10.2147/CCID.S361884. eCollection 2022.

Abstract

Psoriasis is a well-known chronic disease characterized by the development of erythematous, indurated, scaly, pruritic plaques on the skin with cycles of remission and symptom flare-ups. The management of patients with chronic plaque psoriasis has been more challenging since the Covid-19 pandemic as health care professionals have had to adapt to remote consultations for some patients, and patients have had to adapt to the changing health landscape. The rapid resolution of psoriasis symptoms especially those with a substantial impact on quality of life can improve patient satisfaction and adherence, making it an important factor in successful treatment. Cal/BD foam contributes to improved patient adherence and treatment outcome through its rapid action and superior efficacy versus Cal or BD monotherapy, Cal/BD ointment and gel and clobetasol cream in the short-term flare treatment of psoriasis. Moreover, the benefits of proactive long-term management of psoriasis compared to reactive management and its favourable safety profile are higher efficacy and a better health-related quality of life. Cal/BD foam should be considered an effective topical treatment for short-term flare treatment and long-term control of adult psoriatic patients.

摘要

银屑病是一种众所周知的慢性疾病,其特征是皮肤上出现红斑、硬结、鳞屑、瘙痒性斑块,并伴有缓解期和症状复发周期。自新冠疫情以来,慢性斑块状银屑病患者的管理变得更具挑战性,因为医护人员不得不适应对部分患者进行远程会诊,而患者也不得不适应不断变化的健康状况。银屑病症状的快速缓解,尤其是那些对生活质量有重大影响的症状的缓解,可以提高患者满意度和依从性,这使其成为成功治疗的一个重要因素。在银屑病短期发作治疗中,与钙泊三醇或倍他米松单药治疗、钙泊三醇/倍他米松软膏和凝胶以及丙酸氯倍他索乳膏相比,钙泊三醇/倍他米松泡沫剂因其快速起效和卓越疗效,有助于提高患者依从性和治疗效果。此外,与被动管理相比,银屑病主动长期管理的益处及其良好的安全性在于更高的疗效和更好的健康相关生活质量。钙泊三醇/倍他米松泡沫剂应被视为成人银屑病患者短期发作治疗和长期控制的一种有效局部治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5a5/9075015/7031d975007b/CCID-15-809-g0001.jpg

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