Karthikeyan Kaliaperumal, Aishwarya Manju, Elayaperumal Suguna
Department of Dermatology, Venereology and Leprosy and Community Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
Int J Trichology. 2022 Mar-Apr;14(2):55-59. doi: 10.4103/ijt.ijt_157_20. Epub 2022 Apr 4.
Pediculosis is a common ectoparasitic infestation in children. There are different treatment modalities that have been used in the treatment of pediculosis capitis from time immemorial, each with their own shortcomings. Increasing emergence of resistance to permethrin has led to the lookout for newer alternatives.
The role of topical ivermectin in the management of pediculosis in people with culturally different hair grooming practices is analyzed in this study.
This observational open-label clinical study was conducted in September-November 2019 in the schools that were under the rural health center at South India among school-going female children aged between 13 and 16 years of age and diagnosed with pediculosis.
This study demonstrated that a single application of ivermectin shampoo was able to kill head lice in 86.2% of the participants. In participants with persistent infection (13.8%), a repeat application killed the entire louse and 100% efficacy was demonstrated. Topical ivermectin is devoid of systemic side effects of oral ivermectin. Topical ivermectin has found to be more effective than contemporary recommended agents such as malathion and permethrin.
头虱病是儿童常见的体表寄生虫感染。自古以来，治疗头虱病使用了不同的治疗方法，每种方法都有其自身的缺点。对氯菊酯耐药性的不断出现促使人们寻找新的替代方法。
本研究分析了局部用伊维菌素在具有不同文化背景头发护理习惯人群头虱病管理中的作用。
这项观察性开放标签临床研究于2019年9月至11月在印度南部农村卫生中心下属的学校中，对13至16岁被诊断为头虱病的在校女童进行。
本研究表明，单次使用伊维菌素洗发水能够杀死86.2%参与者的头虱。在持续感染的参与者（13.8%）中，重复使用杀死了所有虱子，显示出100%的疗效。局部用伊维菌素没有口服伊维菌素的全身副作用。已发现局部用伊维菌素比马拉硫磷和氯菊酯等当代推荐药物更有效。
