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锁骨致密性骨炎。文献综述及三例报告

Condensing osteitis of the clavicle. A review of the literature and report of three cases.

作者信息

Kruger G D, Rock M G, Munro T G

出版信息

J Bone Joint Surg Am. 1987 Apr;69(4):550-7.

PMID:3553197
Abstract

Condensing osteitis of the clavicle is a rare and benign idiopathic entity that is probably degenerative or mechanical in etiology. It is usually seen in women of late child-bearing age as a variably painful and tender swelling over the medial end of the clavicle. Radiographs show sclerosis and slight expansion of the medial one-third of the clavicle. Although malignant tumor of bone must be considered in the differential diagnosis of a disease that has such radiographic findings, numerous and expensive screening tests for a presumed primary malignant lesion are not recommended for most patients. It is recommended, however, that an excisional or (preferably) incisional biopsy be performed in all patients unless pain is insignificant and the clinical presentation strongly supports the diagnosis of condensing osteitis. Many patients who have slight pain do not need treatment. Anti-inflammatory medications are variably effective. Patients in whom the lesion is refractory respond well to excision of the medial one-third of the clavicle.

摘要

锁骨致密性骨炎是一种罕见的良性特发性疾病,其病因可能为退行性或机械性。它通常见于晚育年龄的女性,表现为锁骨内侧端有程度不一的疼痛和压痛性肿胀。X线片显示锁骨内侧三分之一硬化并略有增宽。尽管在鉴别诊断具有此类X线表现的疾病时必须考虑骨恶性肿瘤,但不建议对大多数患者进行大量且昂贵的针对假定原发性恶性病变的筛查检查。然而,建议对所有患者进行切除活检或(最好是)切开活检,除非疼痛轻微且临床表现强烈支持致密性骨炎的诊断。许多轻度疼痛的患者无需治疗。抗炎药物的效果不一。病变难治的患者对锁骨内侧三分之一切除反应良好。

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