Shiv Shanker V, Paterson J M, Dodd S
Department of Trauma, Royal London Hospital, London, United Kingdom.
J Pediatr Orthop B. 1999 Jan;8(1):48-9.
A 9-year-old boy had a spontaneous onset of enlargement of the medial end of the clavicle due to extensive sclerosis and periosteal reaction. There was no clinical or laboratory evidence of infection. Biopsy revealed an inflammatory exudate, and histochemical staining for Langerhans'-cell histiocytosis was negative. Hypertrophic sclerosis causing painful enlargement of the medial end of the clavicle in isolation should be distinguished from condensing osteitis and chronic recurrent multifocal osteomyelitis. An early biopsy to exclude neoplasia is recommended.
一名9岁男孩因广泛硬化和骨膜反应，锁骨内侧端自发肿大。无感染的临床或实验室证据。活检显示有炎性渗出物，朗格汉斯细胞组织细胞增多症的组织化学染色为阴性。孤立性肥厚性硬化导致锁骨内侧端疼痛性肿大应与骨炎和慢性复发性多灶性骨髓炎相鉴别。建议早期活检以排除肿瘤。
