*Keisuke Seki, DDS, PhD, Clinical Associate Professor, Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry, Tokyo, Japan, Division of Dental Education, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan.
**Shuichi Sato, DDS, PhD, Professor, Department of Periodontology, Nihon University School of Dentistry, Tokyo, Japan, Division of Advanced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan.
J Clin Pediatr Dent. 2022 Mar 1;46(2):119-124. doi: 10.17796/1053-4625-46.2.5.
Few long-term reports exist concerning the treatment of idiopathic gingival fibromatosis, which is a rare autosomal dominant genetic disorder associated with non-inflammatory, benign, and chronic fibrous gingival proliferation and which causes serious esthetic problems. The aim of this study was to report a case of idiopathic gingival fibromatosis treated with a gingivectomy using an inverse bevel flap method and comprehensively followed up for 15 years. A female patient visited a pediatric dentist at 7 years of age; however, a gingivectomy was not performed until the age of 20 years because of an uncertain prognosis. Now, more than 15 years after the gingivectomy, there has been no significant recurrence and the disease is well managed. Treatment by gingivectomy with an inverse bevel flap approach may provide long-term prevention of recurrence of gingival fibromatosis into adulthood. The aim of this study was to obtain new findings on the pathogenesis and prognosis of this rare disease and to review the case reports previously published.
关于特发性牙龈纤维瘤病的治疗，目前仅有少数长期报告，特发性牙龈纤维瘤病是一种罕见的常染色体显性遗传性疾病，与非炎症性、良性和慢性纤维性牙龈增生有关，并导致严重的美观问题。本研究的目的是报告一例采用反斜角瓣法行牙龈切除术治疗的特发性牙龈纤维瘤病病例，并进行了 15 年的综合随访。一名女性患者在 7 岁时就诊于儿科牙医，但由于预后不确定，直到 20 岁才进行牙龈切除术。现在，牙龈切除术已经过去 15 年多了，没有明显的复发，疾病得到了很好的控制。采用反斜角瓣法行牙龈切除术可能为成年期牙龈纤维瘤病的长期预防复发提供了帮助。本研究的目的是获得这种罕见疾病的发病机制和预后的新发现，并对以往发表的病例报告进行回顾。
