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界线类麻风多次复发——病例报告

Multiple relapses in borderline leprosy--a case report.

作者信息

Ramachandran A, Seshadri P S

出版信息

Indian J Lepr. 1986 Oct-Dec;58(4):623-5.

PMID:3553362
Abstract

A case of borderline lepromatous leprosy with a history of 5 years duration of disease, was first seen in 1971 and treated with graded doses of dapsone in the OP Clinic of the Institute. He became inactive and bacteriologically negative in 3 years. While continuing on dapsone therapy he relapsed into active dapsone resistant leprosy 3 1/2 years later. He was admitted in the hospital and given Rifampicin 600 mg. daily for 15 days along with dapsone 100 mg. daily. He again became inactive and bacteriologically negative within 3 years. 3 years later under regular dapsone therapy he relapsed again for the second time into active BT leprosy, but remained bacteriologically negative. He was given 3 drug regimen subsequently and became clinically inactive within 15 months.

摘要

一例边缘性瘤型麻风患者,病程5年,于1971年首次就诊,在该研究所门诊接受了不同剂量的氨苯砜治疗。3年后病情静止,细菌学检查转为阴性。在继续服用氨苯砜治疗期间,3年半后复发为耐氨苯砜的活动性麻风。他入院后,每天给予利福平600毫克,共15天,同时每天给予氨苯砜100毫克。3年内他再次病情静止,细菌学检查转为阴性。3年后,在常规氨苯砜治疗下,他再次复发为活动性BT麻风,但细菌学检查仍为阴性。随后给予三联药物治疗,15个月内临床症状消失。

相似文献

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Multiple relapses in borderline leprosy--a case report.界线类麻风多次复发——病例报告
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[Resistance of Mycobacterium leprae to dapsone and rifampicin: apropos of a survey carried out in the Cape Verde region (Senegal)].[麻风分枝杆菌对氨苯砜和利福平的耐药性:关于在佛得角地区(塞内加尔)开展的一项调查]
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Once monthly rifampicin (1200 mg) plus daily dapsone (100 mg) and clofazimine (100 mg) in the initial treatment of lepromatous leprosy.在瘤型麻风的初始治疗中,每月一次服用利福平(1200毫克),同时每日服用氨苯砜(100毫克)和氯法齐明(100毫克)。
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