生或死——线粒体过程如何影响 Podospora anserina 的寿命。
To die or not to die - How mitochondrial processes affect lifespan of Podospora anserina.
机构信息
Institute of Molecular Biosciences, J. W. Goethe University, Frankfurt am Main, Germany.
出版信息
Biochim Biophys Acta Bioenerg. 2022 Aug 1;1863(6):148568. doi: 10.1016/j.bbabio.2022.148568. Epub 2022 May 6.
The filamentous ascomycete Podospora anserina is a well-established model system to study organismic aging. Its senescence syndrome has been investigated for more than fifty years and turned out to have a strong mitochondrial etiology. Several different mitochondrial pathways were demonstrated to affect aging and lifespan. Here, we present an update of the literature focusing on the cooperative interplay between different processes.
丝状子囊菌 Podospora anserina 是研究机体衰老的成熟模式生物系统。其衰老综合征已被研究了五十多年，结果表明其具有强烈的线粒体病因。有几种不同的线粒体途径被证明会影响衰老和寿命。在这里，我们重点介绍文献更新，关注不同过程之间的协同相互作用。
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