Unità Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital, Castel Volturno, Italy.
Unità Operativa di Emodinamica, Santa Lucia Hospital, San Giuseppe Vesuviano, Italy.
Sci Rep. 2022 May 9;12(1):7612. doi: 10.1038/s41598-022-11788-3.
Transcatheter aortic valve implantation (TAVI) requires thorough preprocedural planning with non-invasive imaging, including computed tomography (CT). The plethora of details obtained with thoraco-abdominal CT represents a challenge for accurate and synthetic decision-making. We devised and tested a comprehensive score suitable to summarize CT exams when planning TAVI. An original comprehensive scoring system (TAVI-CT score) was devised, including details on cardiac, aortic, iliac and femoral artery features. The score was applied to a prospectively collected series of patients undergoing TAVI at our institution, driving decision making on access and prosthesis choice. Different TAVI-CT score groups were compared in terms of procedural success, acute complications, and early clinical outcomes. We included a total of 200 undergoing TAVI between February 2020 and May 2021, with 74 (37.0%) having a low (0-2) TAVI-CT score, 50 (25.0%) having a moderate (3) TAVI-CT score, and 76 (38.0%) having a high (≥ 4) TAVI-CT score. Male gender was the only non-CT variable significantly associated with the TAVI-CT score (p = 0.001). As expected, access choice differed significantly across TAVI-CT scores (p = 0.009), as was device choice, with Portico more favored and Allegra less favored in the highest TAVI-CT score group (p = 0.036). Acute outcomes were similar in the 3 groups, including device and procedural success rates (respectively p = 0.717 and p = 1). One-month follow-up showed similar rates of death, myocardial infarction, stroke, and bleeding, as well as of a composite safety endpoint (all p > 0.05). However, vascular complications were significantly more common in the highest TAVI-CT score group (p = 0.041). The TAVI-CT score is a simple scoring system that could be routinely applied to CT imaging for TAVI planning, if the present hypothesis-generating findings are confirmed in larger prospective studies.
经导管主动脉瓣植入术(TAVI)需要进行彻底的术前规划,包括非侵入性影像学检查,如计算机断层扫描(CT)。胸腹部 CT 获得的大量细节为准确和综合的决策制定带来了挑战。我们设计并测试了一种全面的评分系统,用于总结 TAVI 规划中的 CT 检查。我们设计了一种原始的综合评分系统(TAVI-CT 评分),其中包括心脏、主动脉、髂动脉和股动脉特征的详细信息。该评分系统应用于我们机构前瞻性收集的一系列接受 TAVI 的患者,指导入路和假体选择的决策。根据不同的 TAVI-CT 评分组,比较了手术成功率、急性并发症和早期临床结局。我们共纳入了 200 例 2020 年 2 月至 2021 年 5 月间接受 TAVI 的患者,其中 74 例(37.0%)的 TAVI-CT 评分为低(0-2)分,50 例(25.0%)为中(3)分,76 例(38.0%)为高(≥4)分。男性是唯一与 TAVI-CT 评分显著相关的非 CT 变量(p=0.001)。正如预期的那样,TAVI-CT 评分在入路选择上存在显著差异(p=0.009),而在器械选择上也存在显著差异,Portico 在 TAVI-CT 评分最高的组中更为受欢迎,而 Allegra 则不受欢迎(p=0.036)。3 组的急性结局相似,包括器械和手术成功率(分别为 p=0.717 和 p=1)。1 个月的随访显示,死亡率、心肌梗死、卒中和出血以及复合安全终点的发生率相似(均 p>0.05)。然而,在 TAVI-CT 评分最高的组中,血管并发症更为常见(p=0.041)。TAVI-CT 评分是一种简单的评分系统,如果本研究的假设生成结果在更大的前瞻性研究中得到证实,那么它可以常规应用于 TAVI 规划的 CT 成像。