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TAVI-CT 评分评估行经导管主动脉瓣植入术患者的解剖风险。

TAVI-CT score to evaluate the anatomic risk in patients undergoing transcatheter aortic valve implantation.

机构信息

Unità Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital, Castel Volturno, Italy.

Unità Operativa di Emodinamica, Santa Lucia Hospital, San Giuseppe Vesuviano, Italy.

出版信息

Sci Rep. 2022 May 9;12(1):7612. doi: 10.1038/s41598-022-11788-3.

Abstract

Transcatheter aortic valve implantation (TAVI) requires thorough preprocedural planning with non-invasive imaging, including computed tomography (CT). The plethora of details obtained with thoraco-abdominal CT represents a challenge for accurate and synthetic decision-making. We devised and tested a comprehensive score suitable to summarize CT exams when planning TAVI. An original comprehensive scoring system (TAVI-CT score) was devised, including details on cardiac, aortic, iliac and femoral artery features. The score was applied to a prospectively collected series of patients undergoing TAVI at our institution, driving decision making on access and prosthesis choice. Different TAVI-CT score groups were compared in terms of procedural success, acute complications, and early clinical outcomes. We included a total of 200 undergoing TAVI between February 2020 and May 2021, with 74 (37.0%) having a low (0-2) TAVI-CT score, 50 (25.0%) having a moderate (3) TAVI-CT score, and 76 (38.0%) having a high (≥ 4) TAVI-CT score. Male gender was the only non-CT variable significantly associated with the TAVI-CT score (p = 0.001). As expected, access choice differed significantly across TAVI-CT scores (p = 0.009), as was device choice, with Portico more favored and Allegra less favored in the highest TAVI-CT score group (p = 0.036). Acute outcomes were similar in the 3 groups, including device and procedural success rates (respectively p = 0.717 and p = 1). One-month follow-up showed similar rates of death, myocardial infarction, stroke, and bleeding, as well as of a composite safety endpoint (all p > 0.05). However, vascular complications were significantly more common in the highest TAVI-CT score group (p = 0.041). The TAVI-CT score is a simple scoring system that could be routinely applied to CT imaging for TAVI planning, if the present hypothesis-generating findings are confirmed in larger prospective studies.

摘要

经导管主动脉瓣植入术(TAVI)需要进行彻底的术前规划,包括非侵入性影像学检查,如计算机断层扫描(CT)。胸腹部 CT 获得的大量细节为准确和综合的决策制定带来了挑战。我们设计并测试了一种全面的评分系统,用于总结 TAVI 规划中的 CT 检查。我们设计了一种原始的综合评分系统(TAVI-CT 评分),其中包括心脏、主动脉、髂动脉和股动脉特征的详细信息。该评分系统应用于我们机构前瞻性收集的一系列接受 TAVI 的患者,指导入路和假体选择的决策。根据不同的 TAVI-CT 评分组,比较了手术成功率、急性并发症和早期临床结局。我们共纳入了 200 例 2020 年 2 月至 2021 年 5 月间接受 TAVI 的患者,其中 74 例(37.0%)的 TAVI-CT 评分为低(0-2)分,50 例(25.0%)为中(3)分,76 例(38.0%)为高(≥4)分。男性是唯一与 TAVI-CT 评分显著相关的非 CT 变量(p=0.001)。正如预期的那样,TAVI-CT 评分在入路选择上存在显著差异(p=0.009),而在器械选择上也存在显著差异,Portico 在 TAVI-CT 评分最高的组中更为受欢迎,而 Allegra 则不受欢迎(p=0.036)。3 组的急性结局相似,包括器械和手术成功率(分别为 p=0.717 和 p=1)。1 个月的随访显示,死亡率、心肌梗死、卒中和出血以及复合安全终点的发生率相似(均 p>0.05)。然而,在 TAVI-CT 评分最高的组中,血管并发症更为常见(p=0.041)。TAVI-CT 评分是一种简单的评分系统,如果本研究的假设生成结果在更大的前瞻性研究中得到证实,那么它可以常规应用于 TAVI 规划的 CT 成像。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0251/9085825/fa877893c1bb/41598_2022_11788_Fig1_HTML.jpg

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