酒精性肝病合并慢加急性肝衰竭患者的肝活检
Liver Biopsy in Patients With Alcohol-Associated Liver Disease With Acute-on-Chronic Liver Failure.
作者信息
Jophlin Loretta, Singal Ashwani K
机构信息
Department of Gastroenterology and Hepatology, University of Louisville, Louisville, KY, USA.
Division of Gastroenterology and Hepatology, Department of Medicine, University of South Dakota Sanford School of Medicine, South Dakota, USA.
出版信息
J Clin Exp Hepatol. 2022 Mar-Apr;12(2):544-550. doi: 10.1016/j.jceh.2021.08.009. Epub 2021 Aug 14.
Abstract
Patients with alcohol-associated liver disease may develop severe forms of presentation of acute-on-chronic liver failure, with a high risk for short-term mortality. Alcoholic hepatitis should be suspected among patients with alcohol-associated liver disease who present with acute-on-chronic liver failure. In this review, we discuss the need and feasibility of liver biopsy in the diagnosis of alcoholic hepatitis and predicting its prognosis among decompensated patients with alcohol-associated liver disease and acute-on-chronic liver failure.
摘要
酒精性肝病患者可能会出现严重形式的慢加急性肝衰竭，短期死亡率风险很高。对于出现慢加急性肝衰竭的酒精性肝病患者，应怀疑其患有酒精性肝炎。在本综述中，我们讨论了肝活检在酒精性肝炎诊断以及预测失代偿期酒精性肝病合并慢加急性肝衰竭患者预后方面的必要性和可行性。
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