Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Selcuk University, Konya, Turkey.
School of Physical Therapy and Rehabilitation, Kırsehir Ahi Evran University, Kırsehir, Turkey.
Adv Respir Med. 2022;90(3):164-170. doi: 10.5603/ARM.a2022.0031. Epub 2022 May 10.
As a "vital sign" of health and functional capacity, gait speed is commonly used. However, there is insufficient evidence for possible determinants of gait speed in patients with asthma. The primary objective of the present study was to determine predictors of gait speed in patients with asthma. The second objective was to determine the cut-off point for the 4-minute Gait Speed (4MGS) to better discriminate asthma control status and physical activity in asthma.
Fifty-seven patients with asthma were included in this cross-sectional study. Demographic and clinic characteristics, pulmonary function, asthma control status (ACT, Asthma Control Test), dyspnea, gait speed (4MGS), physical activity [International Physical Activity Questionnaire-Short Form (IPAQ-SF)] and activities of daily living were evaluated. Stepwise multiple linear regression analysis was used to investigate the possible predictors of gait speed. Receiver operating characteristic (ROC) curve analysis was used to determine whether usual gait speed had a discriminative value.
The stepwise multiple regression analysis revealed that the ACT score and the IPAQ-SF score were significant and independent predictors of the 4MGS in patients with asthma explaining 40% of the variance in 4MGS (p < 0.001). The ROC curve showed a cut-off point of 1.06 m/s for the 4MGS for poorly controlled asthma and physical inactivity (p < 0.05).
Our findings indicate that asthma control status and physical activity can be independent predictors of gait speed in patients with asthma. In addition, gait speed may be discriminative to determine poorly controlled asthma and physical inactivity in patients with asthma.
作为健康和功能能力的“生命体征”，步速通常被使用。然而，对于哮喘患者的步速可能的决定因素，证据不足。本研究的主要目的是确定哮喘患者步速的预测因素。第二个目的是确定 4 分钟步态速度（4MGS）的截止值，以更好地区分哮喘控制状况和哮喘患者的体力活动。
这项横断面研究纳入了 57 名哮喘患者。评估了人口统计学和临床特征、肺功能、哮喘控制状况（ACT，哮喘控制测试）、呼吸困难、步态速度（4MGS）、体力活动[国际体力活动问卷-短表（IPAQ-SF）]和日常生活活动。采用逐步多元线性回归分析来探讨步态速度的可能预测因素。采用受试者工作特征（ROC）曲线分析来确定常规步态速度是否具有区分价值。
逐步多元回归分析显示，ACT 评分和 IPAQ-SF 评分是哮喘患者 4MGS 的显著且独立的预测因素，可解释 4MGS 变异的 40%（p<0.001）。ROC 曲线显示，4MGS 的截止值为 1.06m/s，用于判断哮喘控制不佳和体力活动不足（p<0.05）。
我们的研究结果表明，哮喘控制状况和体力活动是哮喘患者步态速度的独立预测因素。此外，步态速度可能具有区分作用，用于确定哮喘患者的哮喘控制不佳和体力活动不足。
