用于近红外二区光热抗菌治疗的新型共轭小分子基纳米颗粒
Novel conjugated small molecule-based nanoparticles for NIR-II photothermal antibacterial therapy.
作者信息
Jia Wenying, Huang Fangfang, Zhang Qiang, Zhao Linlin, Li Chenxi, Lu Yan
机构信息
School of Materials Science & Engineering, Tianjin Key Laboratory for Photoelectric Materials and Devices, Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, Tianjin University of Technology, Tianjin 300384, China.
College of Chemistry, Nankai University, Tianjin 300071, China.
出版信息
Chem Commun (Camb). 2022 May 26;58(43):6340-6343. doi: 10.1039/d2cc00863g.
Single organic small molecule-based nanoparticles (CNPs) with strong responses within the NIR-II (1000-1350 nm) bio-window were prepared, and successfully applied as a highly efficient photothermal antibacterial agent for the first time. CNPs exhibit an outstanding bacteria inhibition efficiency of almost 100% against ( with a high photothermal conversion efficiency (PTCE) of 49% under NIR-II laser irradiation (1064 nm) for 8 min.
制备了在近红外二区（1000 - 1350纳米）生物窗口内具有强烈响应的基于单一有机小分子的纳米颗粒（CNPs），并首次成功将其用作高效光热抗菌剂。在近红外二区激光（1064纳米）照射8分钟的条件下，CNPs对[具体细菌名称未给出]表现出近100%的出色细菌抑制效率，光热转换效率（PTCE）高达49%。
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