Corroenne Romain, Malekzadeh-Milani Sophie Guiti, Bonnet Damien, Stos Bertrand, Ville Yves, Stirnemann Julien
Maternité et médecine fœtale, hôpital Necker enfants malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France; EA7328, Université de Paris, Institut Imagine, France.
M3C-Necker, Hôpital Necker-Enfants malades, AP-HP, Université de Paris, 149, rue de Sèvres, 75015 Paris, France.
Gynecol Obstet Fertil Senol. 2022 Jul-Aug;50(7-8):553-558. doi: 10.1016/j.gofs.2022.04.009. Epub 2022 May 7.
Aortic stenosis is a complex heart disease that involves the aortic valve and the left ventricle. Impairment of the left ventricle, abnormalities in its size, systolic and diastolic function determine the postnatal outcomes in the same way as the aortic valve. In the most severe forms, the left ventricle cannot provide systemic circulation at birth and the physiology is that of hypoplastic left heart syndrome. Fetal aortic valvuloplasty has been developed in the 90s to prevent in utero progression of aortic stenosis to hypoplastic left heart syndrome. In the present article, the most recently reported data about indications, procedure details and postnatal outcomes were reviewed.
主动脉瓣狭窄是一种涉及主动脉瓣和左心室的复杂心脏病。左心室功能受损、其大小、收缩和舒张功能异常与主动脉瓣一样决定出生后的预后。在最严重的形式中，左心室在出生时无法提供体循环，其生理状态为左心发育不全综合征。胎儿主动脉瓣成形术于20世纪90年代开发，以防止子宫内主动脉瓣狭窄进展为左心发育不全综合征。在本文中，回顾了关于适应证、手术细节和出生后预后的最新报道数据。
