School of Biology and Environmental Science, Faculty of Science, Queensland University of Technology, Brisbane, QLD, Australia.
PeerJ. 2022 May 5;10:e13292. doi: 10.7717/peerj.13292. eCollection 2022.
Mucins are part of the glycoprotein family and the main proteinaceous component of mucus. The sea anemone species, (Phylum Cnidaria) produce large amounts of mucus, which have not been studied in detail. Furthermore, there has only been limited investigation of mucin genes in phylum Cnidaria. Therefore, the aim of current study was to identify and analyse the repertoire mucin genes present in and range of other sea anemone species to document their diversity in this group.
To achieve this aim, we undertook transcriptome sequencing, assembly, and annotation to identify mucin genes in .
The results from this study demonstrated a diverse repertoire of mucin proteins, including mucin1-like, mucin4-like, and a range of mucin-like genes in the range of sea anemone species examined. The domain structure of the identified mucin genes was found to be consistent with the conserved domains found in the homologous proteins of vertebrate species. The discovery of a diverse range of mucin genes in sea anemone species provided a basic reference for future mucin studies in cnidarians and could lead to research into their application in the pharmacological, clinical, and cosmetic industries.
粘蛋白是糖蛋白家族的一部分，也是粘液的主要蛋白质成分。海葵（腔肠动物门）会产生大量的粘液，但这些粘液尚未被详细研究。此外，腔肠动物门的粘蛋白基因也仅有有限的研究。因此，本研究旨在鉴定和分析 中存在的粘蛋白基因谱，并研究其他几种海葵物种中的粘蛋白基因，以记录该类群中粘蛋白基因的多样性。
为了实现这一目标，我们进行了转录组测序、组装和注释，以鉴定 中的粘蛋白基因。
本研究结果表明，在研究的海葵物种中存在多样化的粘蛋白蛋白谱，包括粘蛋白 1 样、粘蛋白 4 样和一系列粘蛋白样基因。鉴定出的粘蛋白基因的结构域结构与脊椎动物同源蛋白中的保守结构域一致。在海葵物种中发现的多样化的粘蛋白基因为腔肠动物的粘蛋白研究提供了基本参考，也可能促使人们对其在药理学、临床医学和化妆品行业的应用进行研究。
