Rutkowski Sven, Si Tieyan, Gai Meiyu, Frueh Johannes, He Qiang
Key Lab of Microsystems and Microstructures Manufacturing, Micro/Nanotechnology Research Center, Harbin Institute of Technology Yikuang Street 2 B1 Harbin 150080 P. R. China
School of Engineering and Materials Science, Queen Mary University of London Mile End, Eng, 215 London E1 4NS UK.
RSC Adv. 2018 Jul 4;8(43):24243-24249. doi: 10.1039/c8ra03490g. eCollection 2018 Jul 2.
Hydrodynamic electrospray ionization jetting was applied for generating and characterizing calcium cross-linked alginate microparticles. These microparticles show different diameters and aspect ratios for three electrospray modes (dripping, conejet and multijet modes), four spraying distances (5, 10, 15 and 20 cm), and six spraying concentrations. Comparing the three different electrospray modes, we found that the conejet mode results in the smallest particle diameters, lowest aspect ratio and smallest variations over the parameter space mentioned above. For all spraying modes, the resultant particle diameters become independent of the spraying distance at a sprayed solute concentration ≥ 2.5%. The aspect ratio of microparticles varies significantly for different spraying modes and distances. An increasing aspect ratio of all spray modes was determined for sodium alginate spraying concentrations ≤ 1.5% and spraying distances of 20 cm; this phenomenon can be explained with the chain ejection effect. This systematic investigation offers a basic database for industrial applications of hydrodynamic electrospray ionization.
采用流体动力电喷雾电离喷射法制备并表征了钙交联海藻酸钠微粒。对于三种电喷雾模式（滴流、锥射流和多射流模式）、四种喷雾距离（5、10、15和20厘米）以及六种喷雾浓度，这些微粒呈现出不同的直径和纵横比。比较这三种不同的电喷雾模式，我们发现锥射流模式产生的颗粒直径最小、纵横比最低，并且在上述参数空间内变化最小。对于所有喷雾模式，当喷雾溶质浓度≥2.5%时，所得颗粒直径与喷雾距离无关。微粒的纵横比因不同的喷雾模式和距离而有显著变化。对于海藻酸钠喷雾浓度≤1.5%且喷雾距离为20厘米的情况，所有喷雾模式的纵横比均增加；这种现象可以用链喷射效应来解释。该系统研究为流体动力电喷雾电离的工业应用提供了一个基础数据库。
