采用改良BEACOPP方案对1型脱髓鞘性遗传性运动和感觉神经病（HMSN1）患者进行晚期霍奇金淋巴瘤的有效治疗。
Effective treatment of advanced Hodgkin lymphoma with a modified BEACOPP regimen for a patient with demyelinating hereditary motor and sensory neuropathy type 1 (HMSN1).
作者信息
Hess Patrick P, Ventura Ferreira Monica S, Rolles Benjamin, Kirschner Martin, Holtbernd Florian, Tometten Mareike, Brümmendorf Tim H, Beier Fabian
机构信息
Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation RWTH Aachen University Aachen Germany.
Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD) Aachen Germany.
出版信息
Clin Case Rep. 2022 May 5;10(5):e05766. doi: 10.1002/ccr3.5766. eCollection 2022 May.
Treatment for Hodgkin lymphoma (HL) in adults comprises substantial risk of chemotherapy-induced peripheral neurotoxicity. Here, we describe the case of patient with Charcot-Marie-Tooth disease or HSMN1 and advanced Hodgkin lymphoma undergoing treatment with modified BEACOPP achieving complete remission without major aggravation of neurological symptoms.
成人霍奇金淋巴瘤（HL）的治疗存在化疗诱导的周围神经毒性的重大风险。在此，我们描述了一名患有夏科-马里-图斯病或遗传性运动感觉神经病1型（HSMN1）且患有晚期霍奇金淋巴瘤的患者，接受改良BEACOPP方案治疗后实现完全缓解，且神经症状未出现重大加重的病例。
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