A surfactant-free microemulsion composed of isopentyl acetate, -propanol, and water.

It has been demonstrated that in the absence of traditional surfactants, microemulsions can form from a ternary mixture of oil, water, and an amphi-solvent. These microemulsions are called surfactant-free microemulsions (SFMEs). To date, only a small number of SFME systems have been reported, and the current understanding of SFMEs is very limited. Herein, we report an SFME consisting of isopentyl acetate (IA), -propanol, and water, in which IA (a simple ester compound) and -propanol are used as the oil phase and amphi-solvent, respectively. The microstructures and structural transition of the SFME were investigated by cyclic voltammetry, fluorescence spectroscopy, and UV-visible spectroscopy techniques. Moreover, three kinds of microstructures, namely, oil-in-water (O/W), bicontinuous (BC), and water-in-oil (W/O), have been identified in the SFME, which are directly verified by cryo-TEM observations. A change in the composition of the SFME may lead to a structural transition from O/W through BC to W/O or , which is similar to the case of traditional surfactant-based microemulsions (SBMEs). To the best of our knowledge, this is the first time that the microstructures and structural transition of an SFME obtained using a simple ester compound as the oil phase have been identified.